Cardocal 5 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cilnidipine |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- management of hypertension
- end-organ protection
- useful in elderly patients
- useful in patients with diabetes
- useful in patients with albuminuria
- useful in patients with chronic kidney disease
Pharmacology
- dihydropyridine calcium-channel blocker
- binds to dihydropyridine binding sites
- inhibits Ca2+ influx
- causes vasodilation
- inhibits Ca2+ influx via N-type voltage dependent calcium channels
- inhibits release of norepinephrine
- suppresses reflex increase in heart rate
Dosage & Administration
- 5-10 mg once daily after breakfast for adults
- maximum dose: 20 mg once daily for adults
- pediatric use safety not established
- initiate therapy with lowest possible dose in elderly (5 mg)
Interaction
- other anti-hypertensive medications
- antipsychotics causing hypotension
- quinidine
- carbamazepine
- phenytoin
- rifampicin
- cimetidine
- erythromycin
Contraindications
- known sensitivity to Cilnidipine or any of the excipients
- cardiogenic shock
- recent MI
- acute unstable angina
- severe aortic stenosis
Side Effects
- dizziness
- flushing
- headache
- hypotension
- peripheral edema
- palpitations
- GI disturbances
- increased micturition frequency
- lethargy
- eye pain
- depression
Pregnancy & Lactation
- contraindicated in pregnant women
- contraindicated in women with possibilities of being pregnant
- avoid administration to nursing mothers
- discontinue lactation if administration is indispensable
Precautions & Warnings
- administer with care in patients with serious hepatic dysfunction
- administer with care in patients with history of serious adverse reactions to calcium antagonists
- gradually decrease dosage during discontinuation under close observation
Therapeutic Class
- calcium-channel blockers
Storage Conditions
- store below 30°C
- protect from light and moisture
- keep away from reach of children