Tofacent XR 11 mg (Tablet (Extended Release))
Unit Price: ৳ 80.00 (1 x 10: ৳ 800.00)
Strip Price: ৳ 800.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tofacitinib |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Ulcerative Colitis
Pharmacology
Partial and reversible janus kinase (JAK) inihibitor
Dosage & Administration
- Tofacitinib 5 mg twice daily
- Tofacitinib 11 mg once daily
- Tofacitinib 10 mg twice daily for ulcerative colitis
Interaction
- Potent inhibitors of Cytochrome P450 3A4 (CYP3A4)
- Moderate inhibition of CYP3A4 and potent inhibition of CYP2C19
- Potent CYP inducers
Side Effects
Upper respiratory tract infections, headache, diarrhea, nasopharyngitis
Pregnancy & Lactation
Pregnancy Category C
Precautions & Warnings
- Avoid use during an active serious infection
- Caution in patients at risk of gastrointestinal perforations
- Recommended laboratory monitoring
- Avoid use with live vaccines
- Do not initiate if certain blood counts are low
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- Higher incidence of infections in elderly population
- Dosage adjustment for renal and hepatic impairment
Therapeutic Class
Immunosuppressant
Storage Conditions
Store below 30°C, protect from light and moisture, keep out of reach of children