Tems 80 mg (Tablet)

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Telmisartan
Company Eskayef pharmaceuticals ltd
Also available as
Tems 40 mg tablet Tems 20 mg tablet

Product Title

  • Tems Tablets 40mg

Categories

  • Hypertension medication
  • Cardiovascular prevention drug

Indications

  • Treatment of essential hypertension in adults
  • Reduction of cardiovascular morbidity in adults with atherothrombotic cardiovascular disease or type 2 diabetes mellitus with documented target organ damage

Pharmacology

  • Non-peptide angiotensin-ll receptor antagonist
  • Blocks vasoconstrictor and aldosterone-secreting effects of angiotensin-ll
  • Greater affinity for the AT1 receptor than for the AT2 receptor
  • Does not inhibit ACE (kininase-ll)

Dosage and Administration

  • Usual starting dose of 40mg once a day
  • Blood pressure response is dose-related over the range of 20 to 80 mg
  • Most antihypertensive effect is apparent within 2 weeks
  • Maximal reduction is generally attained after 4 weeks
  • No initial dosage adjustment necessary for elderly patients or patients with renal impairment
  • May be administered with or without food

Pediatric Use

  • Safety and effectiveness not established

Geriatric Use

  • No overall differences in effectiveness and safety compared to younger patients

Hepatic Impairment

  • Monitor carefully and up titrate slowly in patients with biliary obstructive disorders or hepatic insufficiency

Interactions

  • Increased risk of renal impairment and loss of antihypertensive effect when used with NSAIDs
  • Co-administration with aliskiren in patients with diabetes should be avoided

Contraindications

  • Known hypersensitivity to this product or any of its components

Side Effects

  • Sinus pain and congestion (sinusitis)
  • Back pain
  • Diarrhea
  • Intermittent claudication
  • Skin ulcer

Pregnancy and Lactation

  • Pregnancy Category C (first trimester) and D (second and third trimester)
  • Potential adverse effects on the nursing infant

Precautions and Warnings

  • Avoid fetal or neonatal exposure
  • Hypotension
  • Monitor in patients with impaired hepatic or renal function
  • Avoid concomitant use of an ACE inhibitor and angiotensin receptor blocker

Overdose Effects

  • Hypotension
  • Dizziness
  • Tachycardia
  • Bradycardia
  • Increase in serum creatinine
  • Acute renal failure

Therapeutic Class

  • Angiotensin-ll receptor blocker

Storage Conditions

  • Do not store above 30°C
  • Protect from light and high humidity
  • Keep out of the reach of children

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