Epicet 500 mg/5 ml (IV Infusion)

5 ml ampoule: ৳ 40.00 (1 x 5: ৳ 200.00)

Medicine Details

Category Details
Generic Levetiracetam
Company Renata limited
Also available as
Epicet 500 mg oral solution Epicet 500 mg tablet Epicet 250 mg tablet Epicet xr 500 mg tablet Epicet xr 750 mg tablet Epicet xr 1000 mg tablet Epicet xr 1500 mg tablet

Indications

  • Treatment of partial-onset seizures with or without secondary generalisation in adults and adolescents
  • Treatment of myoclonic seizures in adults and adolescents with Juvenile Myoclonic Epilepsy
  • Treatment of primary generalized tonic-clonic seizures in adults and adolescents with Idiopathic Generalised Epilepsy

Description

  • Precise mechanism(s) of antiepileptic effect is unknown
  • Protection against secondarily generalized activity from focal seizures
  • Inhibition of burst firing without affecting normal neuronal excitability

Dosage

  • Recommended starting dose for adults and adolescents from 16 years of age is 250 mg twice daily
  • Maximum dose is 1500 mg twice daily

Administration

  • Tablets must be taken orally, swallowed with sufficient quantity of liquid
  • Administered in two equally divided doses

Interaction

  • Not influencing serum concentrations of existing antiepileptic medicinal products
  • Possible decrease in methotrexate clearance when administered concomitantly

Contraindications

  • Hypersensitivity to the active substance or other pyrrolidone derivatives or to any of the excipients

Side Effects

  • Most common adverse reactions include somnolence, asthenia, infection, dizziness in adults
  • Fatigue, aggression, nasal congestion, decreased appetite, irritability in pediatric patients

Pregnancy & Lactation

  • Not recommended during pregnancy and breastfeeding
  • Excreted in human breast milk

Precautions & Warnings

  • Dose adjustment may be required in patients with renal impairment
  • Rare cases of decreased blood cell counts described
  • Suicidal thoughts and behaviour reported in patients treated with anti-epileptic agents

Use in Special Populations

  • Adjustment of the dose in elderly patients with compromised renal function
  • Dose must be individualized according to renal function in patients with renal impairment

Overdose Effects

  • Somnolence, agitation, depressed level of consciousness observed with overdoses
  • No specific antidote, treatment will be symptomatic

Therapeutic Class

  • Adjunct anti-epileptic drugs

Storage Conditions

  • Store at a cool temperature not exceeding 25°C and dry place, protected from light

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