Oxcarb XR 600 mg (Tablet (Extended Release))
Unit Price: ৳ 30.00 (5 x 6: ৳ 900.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Oxcarbazepine |
| Company | Renata limited |
| Also available as |
Indications
- Monotherapy or adjunctive therapy in the treatment of partial seizures for adults
- Monotherapy in the treatment of partial seizures in children 4-16 years
- Adjunctive therapy in the treatment of partial seizures in children 2–16 years
Pharmacology
- Exerts its activity through the metabolite derivative of Oxcarbazepine
- Blocks voltage-sensitive sodium channels
- Stabilizes hyper excited neural membranes
- Inhibits repetitive neuronal firing
- Diminishes propagation of synaptic impulses
Dosage & Administration
- Adults: initiate with a dose of 600 mg/day, given twice-a-day
- Maximum recommended daily dose is 2400 mg/day
- Pediatrics: initiation with 8 to 10 mg/kg/day, given twice-a-day
- Maximum maintenance dose for children not to exceed 60 mg/kg/day
Interaction
- Inhibits the enzyme CYP2C19
- Interactions with medicinal products metabolised by CYP2C19
- Concurrent use with hormonal contraceptives
- Decrease in bioavailability of MHD
Contraindications
- Hypersensitivity to the active substance or excipients
Side Effects
- Somnolence
- Headache
- Dizziness
- Diplopia
- Nausea
- Vomiting
- Fatigue
- Hyponatraemia
- Hypersensitivity reactions including rash, pruritus, and anaphylaxis
Pregnancy & Lactation
- May cause serious birth defects when administered during pregnancy
- Excreted in human breast milk
Precautions & Warnings
- Caution with alcohol consumption
- Gradual withdrawal to minimize potential increased seizure frequency
Therapeutic Class
- Adjunct anti-epileptic drugs