Bionex 500 mg (Capsule)
Unit Price: ৳ 16.00 (2 x 10: ৳ 320.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tranexamic acid |
| Company | Biopharma limited |
Product Title
- Bionex Hemostatic Medicine
Categories
- Medicine
- Pharmacology
- Hemostatic
Description
- Preparation of tranexamic acid with antifibrinolytic action for prophylaxis and therapy of various hemorrhagic conditions in medicine, surgery, urology, obstetrics, otorhinolaryngology, stomatology, and oncology.
Dimensions
- Box size: varies by number of capsules or ampoules
Color Options
- Not applicable
Functions
- Prophylaxis
- Therapy
- Antihemorrhagic action
- Clot formation promotion
- Inhibition of plasminogen activation
Materials
- Tranexamic acid
- Aminomethyl-cyclohexanecarboxylic acid
Technical Specifications
- Acute toxicity: extremely low
- Chronic toxicity: almost non-existent
- Well absorbed by oral route
- Excretion mainly by renal route
Design Elements
- Ampoules
- Capsules
Usability Features
- Oral administration
- Parenteral administration (intravenous or intramuscular)
- Low single doses
- Long-lasting effect
Dosage And Administration
- Usual adult dose: 500-1000 mg 3 times daily
- Prophylactic adult dose: 0.5-1 gm orally or 500 mg parenterally
- Therapeutic adult dose: 1-3 gm orally with initial intravenous injection
- Prophylactic child dose: 5-10 mg per kg body weight daily
- Therapeutic child dose: Doubled oral doses or initial intravenous treatment
- No reduction in dosage for elderly unless evidence of renal failure
Interaction
- Incompatible with penicillins
- Antagonistic interaction with thrombolytic drugs
- Potential increase in thrombus formation with estrogen containing drugs
- Avoid direct admixture with whole blood during transfusion
Contraindications
- Known hypersensitivity to the product
- Thromboembolic disease
- Arterial and venous thrombosis
- Endocavitary hemorrhages
- Serious kidney failure
Side Effects
- Sense of fatigue
- Conjunctival irritation
- Nasal blockage
- Itching
- Skin reddening
- Exanthems
- Nausea
- Diarrhea
- Gastric pyrosis
- Rare postural hypotension
- Hypersensitivity reactions
Pregnancy And Lactation
- Avoid administration during known and presumed pregnancy
- Passes into breast milk at low concentration unlikely to have antifibrinolytic effect in infants
Precautions And Warnings
- Use in hyperfibrinolysis cases
- Initiate prophylactic treatment before operation and continue post-operation
- Prolong therapy of hemorrhages after manifestations disappear
- Reduce doses in hematuria to prevent clot formation in urinary tract
- Avoid use in serious renal insufficiency or anuric syndromes
- Use with caution in less serious renal dysfunctions, cardiopathic, and hepatopathic subjects
Therapeutic Class
- Anti-fibrinolytic drugs
- Haemostatic drugs
Storage Conditions
- Store at 15-30°C in a dry place away from light and children's reach