Diablo 850 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Dbl pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Indicated for overweight patients
- Can be used in adults as monotherapy or in combination with other oral antidiabetic agents or insulin
- Can be used in children from 10 years of age and adolescents
- Reduces diabetic complications in overweight type 2 diabetic adult patients treated with metformin as first-line therapy after diet failure
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers both basal and postprandial plasma glucose levels
- Decreases hepatic glucose production
- Decreases intestinal absorption of glucose
- Improves insulin sensitivity by increasing peripheral glucose uptake and utilization
Dosage & Administration
- Dosage must be individualized based on effectiveness and tolerance
- Different dosages for immediate release and extended release tablets
- Doses for adults and children
- Recommendations for renal impaired patients
Interaction
- No interaction information is available about the interaction of Diablo and Furosemide when co-administered chronically
- Diablo may enhance the absorption of Nifedipine
- Potential for interaction with cationic drugs eliminated by renal tubular secretion
- Certain drugs may produce hyperglycemia and affect glycemic control
Contraindications
- Hypersensitivity to the active substance or to any excipients
- Any type of acute metabolic acidosis
- Severe renal failure
- Acute conditions with potential to alter renal function
- Acute or chronic diseases that may cause tissue hypoxia
Side Effects
- Blood and lymphatic system disorders
- Metabolism and nutrition disorders
- Nervous system disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Uncontrolled diabetes during pregnancy is associated with increased risk of congenital abnormalities and perinatal mortality
- Metformin is excreted into human breast milk
- Breastfeeding is not recommended during metformin treatment
Precautions & Warnings
- Substantially excreted by the kidney
- Potential to lower vitamin B12 levels
- Increases risk of hypoglycemia when used in combination with insulin
- Regular monitoring of renal function advised
Use in Special Populations
- Dosage adjustment based on renal function in elderly subjects
- No effect on growth and puberty detected during controlled clinical studies
- Special caution recommended when prescribing to children aged between 10 and 12 years
Overdose Effects
- Hypoglycemia not seen with Diablo doses up to 85 grams
- Lactic acidosis occurred in overdose circumstances
- Lactic acidosis is a medical emergency
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children