Q Ben DS 400 mg (Chewable Tablet)

Unit Price: ৳ 5.00 (6 x 10: ৳ 300.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Albendazole
Company Concord pharmaceuticals ltd

Indications

  • Single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid

Description

  • Benzimidazole anthelmintic
  • Active against most nematodes and some cestodes
  • Used in the treatment of intestinal nematode infections
  • Exhibits vermicidal, ovicidal, and larvicidal activity
  • Inhibitory effect on tubulin polymerization

Pharmacology

  • Broad spectrum anthelmintic
  • Exhibits vermicidal, ovicidal, and larvicidal activities
  • Blocks glucose uptake in susceptible helminths
  • Depletes energy level for survival
  • Binding and inhibition of parasite tubulin polymerization
  • Extensively metabolized in the liver
  • Poorly absorbed from the gastrointestinal tract

Dosage & Administration

  • Recommended doses for adults and children
  • Specific doses for different types of infections
  • Doses for hydatid disease
  • Treatment duration and dosage adjustments based on weight
  • Usage in giardiasis

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not normally used in neonates
  • Potential dose reduction for children weighing less than 10 kg
  • Not recommended during pregnancy or lactation
  • No evidence to suggest dose alteration in concurrent diseases

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Rarely reversible alopecia
  • Rash
  • Fever
  • Blood disorders including leucopenia and pancytopenia
  • Allergic shock if cyst leakage
  • Convulsions and meningism in cerebral disease

Pregnancy & Lactation

  • US FDA Pregnancy category of Albendazole is C
  • Avoided in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Blood counts and liver function tests before and during treatment
  • Breastfeeding precautions
  • Pregnancy exclusion before treatment
  • Constant medical supervision for Echinococcosis treatment

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in a dry place
  • Away from light and heat
  • Keep out of the reach of children

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