Fibrostat 500 mg (Capsule)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tranexamic acid |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Title and Categories
- Fibrostat Hemostatic Medicine
- Medicine
- Pharmaceutical
- Hemostatic
- Antifibrinolytic
- Therapeutic Class
- Haemostatic drugs
Dimensions
N/A
Color Options
N/A
Functions
- Prophylaxis and therapy of hemophtoes
- Digestive hemorrhages
- Hemorrhagic syndromes in leukaemia
- Cirrhosis and hemophilia
- Thrombocytopenic purpura
- Accidents during thrombolytic therapy and transfusion
- Antihemorrhagic therapy during operations of any type and nature
- Prophylaxis and antihemorrhagic therapy of prostatic, vesical and renal surgery
- Post-partum and puerperium hemorrhages
- Hemorrhagic metrophathies
- Functional menometrorrhagias
- Epistaxis
- Antihemorrhagic therapy during maxillofacial operations
- To promote the formation of a fibrin capsule to wall off and inhibit the growth of ovarian tumors
- To reduce bleeding during surgical interventions
Materials
Tranexamic acid (trans-4 aminomethyl-cyclohexanecarboxylic acid)
Technical Specifications
- Antifibrinolytic Action: 10 times more active than conventional hemostatics
- Absorption: Well absorbed by oral route
- Excretion: Mainly by renal route but more slowly than conventional hemostatics
- Toxicity: Acute toxicity extremely low, chronic toxicity almost non-existent
- Effect Onset: 15-30 minutes after administration
- Interactions:
- Incompatible with: Solutions containing penicillins
- Antagonizes: Thrombolytic drugs like Streptokinase & Urokinase
- Potential to Increase Thrombus Formation with: Estrogen-containing drugs like oral contraceptives
- Precaution with: Direct admixture with whole blood during transfusion
Usability Features
- Dosage and Administration:
- Adults: 500-1000 mg 3 times daily for prophylaxis and therapy of hemorrhagic manifestations
- Children: For prophylaxis: 5-10 mg/kg/day; For therapy: 10-20 mg/kg/day
- Elderly patients: No reduction in dosage necessary unless evidence of renal failure
- Storage Conditions: Dry place at 15-30°C, away from light and out of children's reach
- Pregnancy & Lactation: Not to be administered during known and presumed pregnancy; Passes into breast milk to a minimal concentration
Design Elements
N/A
Other Attributes
- Contraindications:
- Hypersensitivity: Known individual hypersensitivity to the product
- Conditions: Thromboembolic disease, arterial and venous thrombosis, endocavitary hemorrhages, serious kidney failure
- Side Effects:
- Common:
- Fatigue
- Conjunctival irritation
- Nasal blockage
- Skin reddening
- Exanthems
- Oral Administration:
- Nausea
- Diarrhea
- Gastric pyrosis
- Rare Cases: Postural hypotension
- Common:
- Precautions & Warnings:
- Usage: In cases of hyperfibrinolysis; 24-hour prophylactic treatment before operation
- Therapy Duration: Prolonged for at least 24 hours after manifestations have disappeared
- Hematuria: Reduce doses to prevent clot formation in the urinary tract
- Avoid Usage In: Serious renal insufficiency or anuric syndromes; Caution in less serious renal dysfunctions, cardiopathic, and hepatopathic subjects