Sperid 1 mg/ml (Oral Solution)

100 ml bottle: ৳ 300.00

Medicine Details

Indications

  • Acute and chronic psychoses
  • Mania
  • Schizophrenia

Pharmacology

  • Selective monoaminergic antagonist
  • High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
  • Binds to alpha1 adrenergic receptors
  • Central serotonin and dopamine antagonism

Dosage & Administration

  • Initial dose of 2 mg in 1-2 divided doses
  • Usual dose range 4-6 mg daily
  • Elderly dosage adjustments
  • Initial dose of 1 mg daily for mania
  • Target dose of 3 mg BID for schizophrenia
  • Dosage adjustments at intervals of not less than 1 week

Interaction

  • Antagonizes effects of levodopa and dopamine agonists
  • Reduces plasma clearance with Carbamazepine
  • May enhance effects of certain antihypertensives

Contraindications

  • Known hypersensitivity to the product

Side Effects

  • Insomnia
  • Agitation
  • Anxiety
  • Headache
  • Drowsiness
  • Impaired concentration
  • Fatigue
  • Blurred vision
  • Constipation
  • Nausea
  • Vomiting
  • Hyperprolactinaemia
  • Tachycardia
  • Hypertension
  • Rash
  • Neurtropenia
  • Thrombocytopenia

Pregnancy & Lactation

  • No established safety for use during human pregnancy
  • Excreted in human breast milk
  • Should not breastfeed while receiving

Precautions & Warnings

  • Preexisting cardiovascular diseases
  • Tardive dyskinesia
  • Renal and hepatic impairment
  • Epilepsy
  • Parkinson's disease
  • Pregnancy

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

Related Brands