Twincard 50 mg+25 mg (Tablet)

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Indications

  • Treatment of hypertension
  • Lowering blood pressure
  • Reducing risk of cardiovascular events
  • Treatment to lower blood pressure

Pharmacology

  • Atenolol as a beta1-selective beta blocker
  • Chlorthalidone as a diuretic
  • Reduction in resting and exercise heart rates
  • Reduction in systolic and diastolic blood pressure
  • Reflex orthostatic tachycardia reduction

Dosage & Administration

  • Initial dose of Atenolol 50 mg and Chlorthalidone 25 mg
  • Adjustable dosage for severe renal impairment
  • Use in elderly subjects

Interaction

  • Potentiation of action with other antihypertensive agents
  • Additive effect with calcium channel blockers
  • Decreased hypotensive effects with prostaglandin synthase inhibiting drugs
  • Increased risk of bradycardia with digitalis glycosides

Contraindications

  • Hypersensitivity to the product
  • Sinus bradycardia
  • Heart block greater than first degree
  • Cardiogenic shock
  • Overt cardiac failure
  • Anuria

Side Effects

  • Bradycardia
  • Cold extremities
  • Postural hypotension
  • Leg pain
  • Dizziness
  • Vertigo
  • Lethargy
  • Depression
  • Diarrhea
  • Nausea
  • Wheeziness
  • Hyperuricemia
  • Restlessness

Pregnancy & Lactation

  • Pregnancy Category D
  • Caution during breastfeeding

Precautions & Warnings

  • Aggravation of peripheral arterial circulatory disorders
  • Periodic serum electrolyte determination

Overdose Effects

  • Symptomatic and supportive treatment
  • Removal of unabsorbed drug
  • Consideration for dehydration and electrolyte imbalance

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Cool and dry storage
  • Protection from light

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