Entrovas 97 mg+103 mg (Tablet)

Unit Price: ৳ 120.00 (4 x 5: ৳ 2,400.00)
Strip Price: ৳ 600.00

Medicine Details

Indications

  • To reduce the risk of cardiovascular death
  • For the treatment of symptomatic heart failure
  • Administered in conjunction with other heart failure therapies

Pharmacology

  • Contains a neprilysin inhibitor
  • Contains an angiotensin receptor blocker
  • Inhibits neprilysin and blocks the angiotensin II type-1 receptor

Dosage & Administration

  • Recommended starting dose for adult heart failure
  • Recommended starting dose for pediatric heart failure
  • Recommended Dose Titration for pediatric patients based on weight

Interaction

  • Dual Blockade of the Renin-Angiotensin-Aldosterone System
  • Potassium-sparing Diuretics
  • NSAIDs
  • Lithium

Contraindications

  • Hypersensitivity to any component
  • History of angioedema related to previous ACE inhibitor or ARB therapy
  • Concomitant use of ACE inhibitors
  • Concomitant use of aliskiren in patients with diabetes

Side Effects

  • Angioedema
  • Hypotension
  • Impaired Renal Function
  • Hyperkalemia
  • Cough
  • Dizziness

Pregnancy & Lactation

  • Safety and effectiveness not established in pediatric patients under 1 year
  • No relevant pharmacokinetic differences in elderly patients
  • No dose adjustment required for mild hepatic impairment
  • Not recommended in patients with severe hepatic impairment
  • No dose adjustment required in patients with mild to moderate renal impairment

Precautions & Warnings

  • May cause angioedema
  • Lowers blood pressure
  • May cause symptomatic hypotension
  • Monitor serum potassium periodically

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No relevant pharmacokinetic differences in elderly patients
  • Starting dose recommendation based on renal impairment
  • Starting dose recommendation based on hepatic impairment

Overdose Effects

  • Limited data available with regard to overdosage
  • Hypotension is the most likely result of overdosage

Storage Conditions

  • Keep in a dry place
  • Store below 30°C
  • Protect from moisture
  • Keep out of the reach of children

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