Entrovas 97 mg+103 mg (Tablet)
Unit Price: ৳ 120.00 (4 x 5: ৳ 2,400.00)
Strip Price: ৳ 600.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sacubitril valsartan |
| Company | Renata limited |
| Also available as |
Indications
- To reduce the risk of cardiovascular death
- For the treatment of symptomatic heart failure
- Administered in conjunction with other heart failure therapies
Pharmacology
- Contains a neprilysin inhibitor
- Contains an angiotensin receptor blocker
- Inhibits neprilysin and blocks the angiotensin II type-1 receptor
Dosage & Administration
- Recommended starting dose for adult heart failure
- Recommended starting dose for pediatric heart failure
- Recommended Dose Titration for pediatric patients based on weight
Interaction
- Dual Blockade of the Renin-Angiotensin-Aldosterone System
- Potassium-sparing Diuretics
- NSAIDs
- Lithium
Contraindications
- Hypersensitivity to any component
- History of angioedema related to previous ACE inhibitor or ARB therapy
- Concomitant use of ACE inhibitors
- Concomitant use of aliskiren in patients with diabetes
Side Effects
- Angioedema
- Hypotension
- Impaired Renal Function
- Hyperkalemia
- Cough
- Dizziness
Pregnancy & Lactation
- Safety and effectiveness not established in pediatric patients under 1 year
- No relevant pharmacokinetic differences in elderly patients
- No dose adjustment required for mild hepatic impairment
- Not recommended in patients with severe hepatic impairment
- No dose adjustment required in patients with mild to moderate renal impairment
Precautions & Warnings
- May cause angioedema
- Lowers blood pressure
- May cause symptomatic hypotension
- Monitor serum potassium periodically
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No relevant pharmacokinetic differences in elderly patients
- Starting dose recommendation based on renal impairment
- Starting dose recommendation based on hepatic impairment
Overdose Effects
- Limited data available with regard to overdosage
- Hypotension is the most likely result of overdosage
Storage Conditions
- Keep in a dry place
- Store below 30°C
- Protect from moisture
- Keep out of the reach of children