R-Zol 400 mg (Chewable Tablet)

Unit Price: ৳ 4.00 (25's pack: ৳ 100.00)

Medicine Details

Category Details
Generic Albendazole
Company Reman drug laboratories ltd

Indications

  • Single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid

Description

  • Benzimidazole anthelmintic
  • Active against most nematodes and some cestodes
  • Vermicidal, ovicidal, and larvicidal activity
  • Inhibitory effect on tubulin polymerization

Pharmacology

  • Broad spectrum anthelmintic
  • Exhibits vermicidal, ovicidal, and larvicidal activities
  • Blocks glucose uptake in susceptible helminths
  • Depletes energy level in helminths
  • Binds and inhibits parasite tubulin polymerization

Dosage & Administration

  • Recommended doses for adults, children over 2 years, and children of 1-2 years
  • Special dosage for patients with hydatid disease
  • Treatment regimen for cystic echinococcosis and alveolar echinococcosis

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not recommended for neonates
  • Possible dose reduction for children under 10 kg
  • Avoid use in pregnant women
  • No evidence for altered dosage in renal, hepatic, or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Reversible alopecia (rare)
  • Rash
  • Fever
  • Blood disorders including leucopenia and pancytopenia
  • Allergic shock if cyst leakage
  • Convulsion and meningism in cerebral disease

Pregnancy & Lactation

  • US FDA Pregnancy category C
  • Avoid in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Blood counts and liver function tests before treatment and during cycles
  • Considerations for breastfeeding women
  • Exclude pregnancy before starting treatment
  • Constant medical supervision for treatment of Echinococcosis

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in a dry place, away from light and heat
  • Keep out of the reach of children

Related Brands