R-Zol 400 mg (Chewable Tablet)
Unit Price: ৳ 4.00 (25's pack: ৳ 100.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Reman drug laboratories ltd |
Indications
- Single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid
Description
- Benzimidazole anthelmintic
- Active against most nematodes and some cestodes
- Vermicidal, ovicidal, and larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Exhibits vermicidal, ovicidal, and larvicidal activities
- Blocks glucose uptake in susceptible helminths
- Depletes energy level in helminths
- Binds and inhibits parasite tubulin polymerization
Dosage & Administration
- Recommended doses for adults, children over 2 years, and children of 1-2 years
- Special dosage for patients with hydatid disease
- Treatment regimen for cystic echinococcosis and alveolar echinococcosis
Interaction
- No reported pharmacodynamic or pharmacokinetic interactions
Contraindications
- Not recommended for neonates
- Possible dose reduction for children under 10 kg
- Avoid use in pregnant women
- No evidence for altered dosage in renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Reversible alopecia (rare)
- Rash
- Fever
- Blood disorders including leucopenia and pancytopenia
- Allergic shock if cyst leakage
- Convulsion and meningism in cerebral disease
Pregnancy & Lactation
- US FDA Pregnancy category C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Blood counts and liver function tests before treatment and during cycles
- Considerations for breastfeeding women
- Exclude pregnancy before starting treatment
- Constant medical supervision for treatment of Echinococcosis
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in a dry place, away from light and heat
- Keep out of the reach of children