Renocal Plus 435 mg+ 235 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Calcium acetate magnesium carbonate |
| Company | Everest pharmaceuticals ltd |
Indications
- Treatment of hyperphosphatemia
- Chronic renal insufficiency
- Dialysis patients
- Adults
Composition
- Calcium acetate 110mg
- Magnesium carbonate 60mg
Pharmacology
- Phosphate-binding compounds
- Low solubility salts formation
- Excretion with faeces
- Maximal binding capacity at pH 6-8
Dosage & Administration
- 3-10 tablets per day for adults
- Subdivided dose based on meals
- Starting dose of 3 tablets
- Maximum dose of 12 tablets
- Not recommended for children
- Must be taken with meals
- Should not be crushed or chewed
- Administered 2 hours before or 3 hours after other oral medications
Interaction
- Interferes with antibiotic absorption
- Affects iron absorption
- Adsorbs digoxin
- Decreases nitrofurantoin absorption
- Reduces penicillamine absorption
- Affects levothyroxine absorption
- Influences calcium and vitamin D absorption
- Interacts with oestrogens and calcium antagonists
Contraindications
- Hypophosphataemia
- Hypercalcaemia
- Elevated serum magnesium levels
- AV-block III
- Myasthenia gravis
- Hypersensitivity
Side Effects
- Soft stools
- Gastrointestinal irritation
- Nausea
- Anorexia
- Constipation
- Diarrhoea
- Asymptomatic or symptomatic hypercalcaemia
- Asymptomatic hypermagnesaemia
Pregnancy & Lactation
- Limited data on pregnant women
- Not recommended during pregnancy
- Excreted in human milk
- Breast-feeding not recommended
Precautions & Warnings
- Requires dietary consultation prior to use
- Continuous monitoring of serum calcium, magnesium, and phosphate
- Administer with caution for severe hyperphosphataemia
- Continuous monitoring of serum phosphate, magnesium, and calcium
- Long-term use may result in hypermagnesaemia
- Patients should seek medical advice before taking antacids
- May lead to hypercalcaemic episodes in chronic renal insufficiency patients
- Monitoring of symptoms and possible soft tissue calcifications
- Not recommended for children and adolescents
Overdose Effects
- Suppresses neural activity
- Systemic toxicity at serum concentration of 2.5 mmol/l
- Gastrointestinal disturbances
- Muscle weakness
- Arterial hypotension induced by vasodilatation
- Respiratory and cardiac arrest at serum levels above 10 mmol/l
- Symptoms of hypercalcaemia including muscle weakness, gastrointestinal disturbances, arrhythmia, and psychosis
- Long-term overdosing may lead to adynamic osteopathy
- Emergency treatment involves symptomatic and dialysate magnesium-concentration reduction
Therapeutic Class
- Specific mineral preparations
Storage Conditions
- Keep below 30°C
- Away from light and moisture
- Keep out of the reach of children