Tracid 500 mg/5 ml (IM/IV Injection)

5 ml ampoule: ৳ 65.00 (1 x 3: ৳ 195.00)

Medicine Details

Category	Details
Generic	Tranexamic acid
Company	Acme laboratories ltd
Also available as	Tracid 500 mg tablet Tracid 650 mg tablet

Indications

Prophylaxis and therapy of hemoptysis
Digestive hemorrhages
Hemorrhagic syndromes in leukemia
Cirrhosis and hemophilia
Thrombocytopenic purpura
Accidents during thrombolytic therapy and transfusion

Pharmacology

Strong antifibrinolytic action
10 times more active than conventional hemostatics
Inhibition of plasminogen activation
Low acute and chronic toxicity
Well absorbed by oral route
Excretion mainly by renal route
No interference with clotting processes

Dosage & Administration

Usual adult dose: 500-1000 mg 3 times daily
Mean recommended daily doses for prophylaxis: 0.5-1 gm orally, 500 mg by parenteral route
Increased oral dose for therapy of hemorrhagic manifestations: 1-3 gm in divided doses

Interaction

Incompatible with solutions containing penicillins
Thrombolytic drugs antagonize the antifibrinolytic action
Potential for increased thrombus formation with concomitant estrogen-containing drugs
Avoid direct admixture with whole blood during transfusion

Contraindications

Individual hypersensitivity
Thromboembolic disease
Serious kidney failure

Side Effects

Fatigue
Conjunctival irritation
Nasal blockage
Nausea
Diarrhea
Postural hypotension

Pregnancy & Lactation

Avoid administration during known and presumed pregnancy
Passes into breast milk to a low concentration

Precautions & Warnings

Use in cases of hyperfibrinolysis
Begin prophylactic treatment 24 hours before operation
Prolong therapy of hemorrhages for at least 24 hours after disappearance
Reduce doses in hematuria to prevent clot formation in urinary tract
Use with caution in renal and hepatic dysfunctions

Therapeutic Class

Anti-fibrinolytic drugs
Haemostatic drugs

Storage Conditions

Store in a dry place at 15-30°C
Away from light
Keep out of children's reach

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