Pase OFT 0.5 mg (Flash Tablet)
Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
- Adjunct in the treatment of the petit mal variant of Lennox-Gastaut Syndrome
- Usability for patients who have failed to respond to succinimides
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Positive allosteric modulation of GABA receptor
- Effect on serotonin levels
- Suppression of paroxysmal activity in seizures
Dosage & Administration
- Initial dose for adults with seizure disorders
- Initial dose for adults with panic disorder
- Initial dose for pediatric patients
- Dosage for intravenous administration in infants, children, and adults
Interaction
- Effect on the metabolism of phenytoin, carbamazepine, and phenobarbital
- Lack of investigation on the effect on the metabolism of other drugs
Contraindications
- History of hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Acute narrow angle glaucoma
Side Effects
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Coma
- Tremor
- Vertigo
- Confusion
- Depression
- Amnesia
- Hallucinations
- Hysteria
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential of producing congenital malformations
- Potential for drug to act as teratogen
- Recommendation to administer only if benefits outweigh the risks
- Advice to discontinue breastfeeding if compelling indication for use exists
Precautions & Warnings
- Potential to increase incidence or precipitate the onset of generalized tonic-clonic seizures
- Concomitant use with valproic acid leading to absence status
Use in Special Populations
- Saliva and bronchial secretion increase in infants and small children
- Greater pharmacologic effects in elderly patients
- Effect of renal impairment on pharmacokinetics
- Difference in plasma protein binding in cirrhotic patients
Overdose Effects
- Symptoms including drowsiness, ataxia, dysarthria, nystagmus
- Potential life-threatening effects if taken with other central nervous system depressants
- Treatment options including monitoring vital signs, administration of activated charcoal, and use of flumazenil
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Instructions for slow intravenous injection
- Instructions for intravenous infusion
- Precautions for intramuscular injection
Storage Conditions
- Precautions for storage away from light and heat
- Advisory to keep out of the reach of children
Chemical Structure
- Molecular formula: C15H10ClN3O3
- Reference to chemical structure image
Common Questions about Pase OFT 0.5 mg Flash Tablet
- Usability as a sleeping pill
- Duration of use as advised by the doctor
- Withdrawal symptoms upon discontinuation
- Identification of early symptoms of suicidal thoughts and actions
- Potential for weight gain
- Effects on memory
- Harmful effects of exceeding recommended doses
- Advisory not to take Pase OFT 0.5 mg Flash Tablet with zolpidem
- Advisory not to take Pase OFT 0.5 mg Flash Tablet with quetiapine
- Additional quick tips for usage and precautions