Arbilon Plus 50 mg+12.5 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Indications

  • Treatment of hypertension
  • Reducing the risk of stroke in hypertensive patients with left ventricular hypertrophy

Pharmacology

  • Losartan blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II
  • Hydrochlorothiazide's effect on renal tubular mechanisms of electrolyte reabsorption

Dosage

  • Usual starting dose of 50/12.5 is one tablet once daily
  • Maximum dose is 100/25 once daily
  • Severe hypertension starting dose of 50/12.5 once daily

Administration

  • May be administered with other antihypertensive agents
  • May be administered with or without food

Interaction

  • No significant drug-drug pharmacokinetic interactions with a range of drugs
  • Potentiation with certain antihypertensive and diuretic drugs

Contraindications

  • Hypersensitivity to any component
  • Anuria or hypersensitivity to sulfonamide-derived drugs

Side Effects

  • Symptomatic hypotension
  • Hyperkalaemia
  • Gastro-intestinal disturbances
  • Angioedema
  • Vertigo
  • Headache

Pregnancy & Lactation

  • Avoided in pregnancy unless essential
  • Not recommended in breastfeeding

Precautions & Warnings

  • Periodic determination of serum electrolytes
  • Impaired renal function
  • Symptomatic hypotension

Use in Special Populations

  • Use in Patients with Renal Impairment
  • Use in Patients with Hepatic Impairment
  • Use in pediatric patients not established

Overdose Effects

  • Likely manifestation of overdosage could be hypotension and tachycardia
  • Supportive treatment for symptomatic hypotension

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Keep out of the reach of children

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