Clonafix 2 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Novatek pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome
- Treatment of petit mal variant seizures
- Adjunct in treatment of myoclonic seizures
- Adjunct in treatment of absence seizures
- Long-term use not systematically studied
Pharmacology
- Anticonvulsive properties
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Effect on serotonin
- Suppression of various types of paroxysmal activity
Dosage & Administration
- Initial dose for adults with seizure disorders
- Maximum recommended daily dose for adults
- Initial dose for adults with panic disorder
- Initial dose for pediatric patients
- Dosage for infants and children
- Dosage for intravenous and intramuscular administration
Interaction
- No alteration of pharmacokinetics of certain drugs
- Effect on the metabolism of other drugs not investigated
Contraindications
- Hypersensitivity to benzodiazepines
- No clinical or biochemical evidence of significant liver disease
- Contraindicated in acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Coma
- Tremor
- Vertigo
- Confusion
- Depression
- Amnesia
- Hallucinations
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential for producing congenital malformations
- Evidence of anticonvulsant drugs acting as teratogens
- Administration during pregnancy only if compelling indication
- Passage into maternal milk
- Discontinuation of breastfeeding if compelling indication for use
Precautions & Warnings
- Possible increase in incidence of generalized tonic-clonic seizures in certain patients
- Concomitant use with valproic acid
- Increased pharmacologic effects in elderly patients
- Unaffected pharmacokinetics in renal impairment
- Significant differences in plasma protein binding in cirrhotic patients
Use in Special Populations
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- Unaffected pharmacokinetics in renal impairment
- Possible reduction in clearance of unbound drug in liver cirrhosis
Overdose Effects
- Common symptoms of overdose
- Potential life-threatening effects if taken with other CNS depressants
- Treatment involving monitoring of vital signs and symptomatic treatment
- Use of flumazenil as a benzodiazepine antagonist under closely monitored conditions
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Requirements for slow intravenous injection
- Requirements for intravenous infusion
- Diluting media for infusion and stability
- Considerations for intramuscular injection
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Chemical Structure Image URL
Common Questions
- Use as a sleeping pill
- Duration of use
- Withdrawal symptoms
- Monitoring for suicidal thoughts
- Effect on weight gain
- Effect on memory
- Harmfulness of overdosage
- Co-administration with other medications
- Quick Tips for usage