Traxyl 500 mg (Capsule)

Unit Price: ৳ 25.00 (3 x 10: ৳ 750.00)
Strip Price: ৳ 250.00

Medicine Details

Category Details
Generic Tranexamic acid
Company Nuvista pharma ltd
Also available as
Traxyl 500 mg injection

Indications

  • Prophylaxis of hemoptysis
  • Therapy of digestive hemorrhages
  • Hemorrhagic syndromes in leukemia
  • Cirrhosis and hemophilia
  • Thrombocytopenic purpura
  • Accidents during thrombolytic therapy and transfusion
  • Prophylaxis and antihemorrhagic therapy during surgery
  • Prophylaxis and antihemorrhagic therapy in urology
  • Prophylaxis and therapy of post-partum and puerperium hemorrhages
  • Prophylaxis and antihemorrhagic therapy in otorhinolaryngology
  • Prophylaxis and antihemorrhagic therapy during dental surgery
  • Supportive therapy in oncology

Pharmacology

  • Tranexamic acid
  • Antifibrinolytic action
  • Inhibition of plasminogen activation
  • Low acute and chronic toxicity
  • Well absorbed by oral route
  • Excretion by renal route
  • No interference with clotting processes

Dosage & Administration

  • Usual adult dose: 500-1000 mg 3 times daily
  • Mean recommended daily doses for prophylaxis: 0.5-1 gm orally, 500 mg parenterally
  • Increased oral dose for therapy of hemorrhagic manifestations
  • Dosage for children based on body weight

Interaction

  • Incompatibility with penicillins
  • Antagonism with thrombolytic drugs
  • Increased potential for thrombus formation with estrogen-containing drugs
  • Avoid direct admixture with whole blood during transfusion

Contraindications

  • Known hypersensitivity to the product
  • Thromboembolic disease
  • Arterial and venous thrombosis
  • Endocavitary hemorrhages
  • Serious kidney failure

Side Effects

  • Sense of fatigue
  • Conjunctival irritation
  • Nasal blockage
  • Skin reactions
  • Nausea
  • Diarrhea
  • Gastric pyrosis
  • Rare cases of postural hypotension

Pregnancy & Lactation

  • Avoid use during known and presumed pregnancy
  • Passage into breast milk at low concentration

Precautions & Warnings

  • Use in hyperfibrinolysis cases
  • Initiate prophylactic treatment before operation
  • Prolong therapy of hemorrhages
  • Adjust doses in hematuria
  • Avoid use in serious renal insufficiency
  • Exercise caution in renal and hepatic dysfunctions

Therapeutic Class

  • Anti-fibrinolytic drugs
  • Haemostatic drugs

Storage Conditions

  • Store at 15-30°C
  • Away from light
  • Keep out of children's reach

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