Traxyl 500 mg (Capsule)
Unit Price: ৳ 25.00 (3 x 10: ৳ 750.00)
Strip Price: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tranexamic acid |
| Company | Nuvista pharma ltd |
| Also available as |
Indications
- Prophylaxis of hemoptysis
- Therapy of digestive hemorrhages
- Hemorrhagic syndromes in leukemia
- Cirrhosis and hemophilia
- Thrombocytopenic purpura
- Accidents during thrombolytic therapy and transfusion
- Prophylaxis and antihemorrhagic therapy during surgery
- Prophylaxis and antihemorrhagic therapy in urology
- Prophylaxis and therapy of post-partum and puerperium hemorrhages
- Prophylaxis and antihemorrhagic therapy in otorhinolaryngology
- Prophylaxis and antihemorrhagic therapy during dental surgery
- Supportive therapy in oncology
Pharmacology
- Tranexamic acid
- Antifibrinolytic action
- Inhibition of plasminogen activation
- Low acute and chronic toxicity
- Well absorbed by oral route
- Excretion by renal route
- No interference with clotting processes
Dosage & Administration
- Usual adult dose: 500-1000 mg 3 times daily
- Mean recommended daily doses for prophylaxis: 0.5-1 gm orally, 500 mg parenterally
- Increased oral dose for therapy of hemorrhagic manifestations
- Dosage for children based on body weight
Interaction
- Incompatibility with penicillins
- Antagonism with thrombolytic drugs
- Increased potential for thrombus formation with estrogen-containing drugs
- Avoid direct admixture with whole blood during transfusion
Contraindications
- Known hypersensitivity to the product
- Thromboembolic disease
- Arterial and venous thrombosis
- Endocavitary hemorrhages
- Serious kidney failure
Side Effects
- Sense of fatigue
- Conjunctival irritation
- Nasal blockage
- Skin reactions
- Nausea
- Diarrhea
- Gastric pyrosis
- Rare cases of postural hypotension
Pregnancy & Lactation
- Avoid use during known and presumed pregnancy
- Passage into breast milk at low concentration
Precautions & Warnings
- Use in hyperfibrinolysis cases
- Initiate prophylactic treatment before operation
- Prolong therapy of hemorrhages
- Adjust doses in hematuria
- Avoid use in serious renal insufficiency
- Exercise caution in renal and hepatic dysfunctions
Therapeutic Class
- Anti-fibrinolytic drugs
- Haemostatic drugs
Storage Conditions
- Store at 15-30°C
- Away from light
- Keep out of children's reach