Intracort 40 mg/ml (IM/IA Injection)

Product title

• Triamcinolone Acetonide Injection

Categories

• Medicine
• Pharmaceutical

Description

• Injectable corticosteroid medication
• Indicated for intramuscular and intra-articular use
• Used as adjunctive therapy for a variety of medical conditions

Color options

• White
• Cream-colored

Dosage form

• Injection
• Suspension

Pharmacology

• Synthetic glucocorticoid corticosteroid
• Anti-inflammatory action
• Practically insoluble in water
• Very soluble in alcohol

Dosage and administration

• Initial dose may vary from 2.5 mg to 100 mg per day
• Suggested initial intramuscular dose is 60 mg
• Strict aseptic technique is mandatory for administration
• For systemic therapy, injection should be deeply into the gluteal muscle
• For intra-articular administration, a single local injection is often sufficient

Contraindications

• Hypersensitivity to any components of the product
• Contraindicated for idiopathic thrombocytopenic purpura

Interaction

• Aminoglutethimide may lead to loss of corticosteroid-induced adrenal suppression
• Concurrent use of corticosteroids and potassium-depleting agents should be observed closely for hypokalemia
• Macrolide antibiotics may cause a significant decrease in corticosteroid clearance
• Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis

Side effects

• Adverse reactions may include allergic reactions, cardiovascular effects, dermatologic effects, endocrine disturbances, fluid and electrolyte disturbances, gastrointestinal effects, metabolic effects, musculoskeletal effects, neurologic/psychiatric effects, ophthalmic effects

Pregnancy and lactation

• Pregnancy category C
• Systemically administered corticosteroids appear in human milk and could suppress growth or interfere with endogenous corticosteroid production
• Caution should be exercised when administered to a nursing woman

Precautions and warnings

• Sensitive to heat, should not be autoclaved for sterilization
• The lowest possible dose should be used to control the condition
• Corticosteroids should be used with caution in patients with cardiac, renal, gastrointestinal, and musculoskeletal conditions

Special populations

• Pediatric use: Premature, low-birth-weight infants, and high dosages may be more likely to develop toxicity
• Geriatric use: No overall differences in safety or effectiveness observed

Overdose effects

• Treatment is by supportive and symptomatic therapy
• For chronic overdosage, dosage may be reduced temporarily or alternate day treatment may be introduced

Therapeutic class

• Corticosteroid
• Glucocorticoids
• Triamcinolone & Combined preparations

Storage conditions

• Store at controlled room temperature (20-25°C)
• Avoid freezing and protect from light

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