Trexam 500 mg/5 ml (IM/IV Injection)

5 ml ampoule: ৳ 80.00 (1 x 5: ৳ 400.00)

Medicine Details

Title and Categories

  • Trexam Capsules
  • Medicine
  • Hemostatic
  • Anti-fibrinolytic drug
  • Pharmaceutical

Dimensions

  • Capsule Size: Standard
  • Package Size: 30 capsules per pack

Color Options

  • White capsules

Functions

  • Prophylaxis of hemoptysis
  • Therapy of hemoptysis
  • Digestive hemorrhage therapy
  • Prophylaxis and antihemorrhagic therapy during surgeries
  • Antihemorrhagic therapy in urology
  • Prophylaxis and therapy of post-partum and puerperium hemorrhages
  • Antihemorrhagic therapy in obstetrics
  • Prophylaxis and antihemorrhagic therapy in otorhinolaryngology
  • Antihemorrhagic therapy in stomatology
  • Supportive therapy in oncology

Materials

  • Tranexamic acid
  • Gelatin (Capsule shell)

Technical Specifications

  • Active Ingredient: Tranexamic Acid
  • Antifibrinolytic Action: Strong
  • Acute Toxicity: Extremely Low
  • Chronic Toxicity: Almost Non-existent
  • Route of Absorption: Oral
  • Excretion: Mainly Renal
  • Effect Onset: 15-30 minutes after administration

Design Elements

  • Capsule Shell: Gelatin
  • Capsule Packaging: Blister Packs

Usability Features

  • Dosage Forms:
    • Capsules
    • Oral Solution
  • Dosage Administration: Oral, Intravenous, Intramuscular
  • Dosage Recommendations:
    • Adults: 500-1000 mg 3 times daily
    • Children: 5-10 mg per kg body weight for prophylaxis

Interaction

  • Incompatible with:
    • Penicillins
  • Antagonizes:
    • Thrombolytic drugs
  • Potential Increased Thrombus Formation with:
    • Estrogen-containing drugs

Contraindications

  • Known individual hypersensitivity
  • Thromboembolic disease
  • Arterial and venous thrombosis
  • Endocavitary hemorrhages
  • Serious kidney failure

Side Effects

  • Sense of fatigue
  • Conjunctival irritation
  • Nasal blockage
  • Itching
  • Skin reddening
  • Exanthems
  • Nausea
  • Diarrhea
  • Gastric pyrosis
  • Rare cases of postural hypotension

Pregnancy & Lactation

  • Pregnancy: Contraindicated
  • Lactation: Passes into breast milk in minimal concentration, unlikely to have antifibrinolytic effect in infant

Precautions & Warnings

  • Use in cases of hyperfibrinolysis
  • Prophylactic treatment initiation before operation
  • Prolonged therapy for hemorrhages
  • Caution in hematuria to prevent clot formation in urinary tract
  • Avoid in serious renal insufficiency
  • Administer with caution in cardiopathic and hepatopathic subjects

Therapeutic Class

  • Anti-fibrinolytic drugs
  • Haemostatic drugs

Storage Conditions

Dry place at 15-30°C, away from light and out of children's reach

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