Cefuxim-CV 500 mg+125 mg (Tablet)

Unit Price: ৳ 66.00 (2 x 7: ৳ 924.00)
Strip Price: ৳ 462.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Albion laboratories limited
Also available as
Cefuxim cv 250 mg tablet

Title

  • Cefuxim-CV 500 mg Tablet

Categories

  • Medicine
  • Antibiotics
  • Infections
  • Bacterial Infections
  • Healthcare

Description

  • Cefuxim-CV 500 mg Tablet is indicated for the treatment of infections caused by sensitive bacteria.

Dosage & Administration

  • 250 mg b.i.d. for 5-10 days for Pharyngitis/Tonsillitis in adults
  • 250-500 mg b.i.d. for 10 days for Uncomplicated skin and skin structure infections in adults
  • 250 mg b.i.d. for 7-10 days for Uncomplicated urinary tract infections in adults
  • 1000 mg b.i.d. Single dose for Uncomplicated Gonorrhoea in adults
  • 20 mg/kg/day b.i.d for 5-10 days for Pharyngitis/Tonsillitis in Paediatric Patients
  • 30 mg/kg/day b.i.d for 10 days for Acute otitis media in Paediatric Patients

Mode of Action

  • Cefuroxime inhibits bacterial cell wall synthesis by interfering with the transpeptidation process.
  • Clavulanic acid irreversibly binds to beta-lactamase enzymes and inactivates them, giving protection to Cefuroxime from degradation.

Interaction

  • Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%.

Contraindications

  • Cefuroxime-Clavulanic Acid is contraindicated in patients with known allergy to cephalosporin & in patients with Pseudomembranous Colitis.

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Prolonged administration may result in overgrowth of nonsusceptible microorganisms
  • Renal dysfunction (rare)
  • Anaphylaxis (rare)
  • Angioedema (rare)
  • Pruritis (rare)
  • Rash (rare)

Pregnancy & Lactation

  • Should be avoided in the first trimester if possible
  • Can be safely used in later pregnancy to treat urinary and other infections
  • Excreted into the breast milk in small quantities.

Precautions & Warnings

  • Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis.

Therapeutic Class

  • Second generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30° C), away from light and moisture. Keep out of the reach of children.

Attributes

  • Bactericidal nature
  • Active against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibits bacterial cell wall synthesis
  • Wide range of indications
  • Treatment for sensitive bacterial infections
  • Cephalosporin antibiotic
  • Beta-lactamase inhibitor
  • Pharyngitis/Tonsillitis treatment
  • Acute Bacterial Otitis Media treatment
  • Acute bacterial maxillary sinusitis treatment
  • Lower respiratory tract infections treatment
  • Skin and skin-structure infections treatment
  • Urinary tract infections treatment
  • Bone and Joint Infections treatment
  • Uncomplicated Gonorrhoea treatment
  • Early Lyme Disease treatment
  • Septicemia treatment
  • Meningitis treatment
  • Switch therapy (Injectable to oral)
  • Adolescents and adults dosage instructions
  • Paediatric Patients dosage instructions
  • Pharmacological mode of action
  • Contraindications for allergy
  • Side effects such as nausea, vomiting, diarrhea
  • Precautions for patients with colitis
  • Storage instructions
  • Pregnancy & lactation usage
  • Therapeutic class
  • Interaction with probenecid
  • Gastric acidity interaction
  • Renal dysfunction rare side effect
  • Anaphylaxis rare side effect
  • Angioedema rare side effect
  • Pruritis rare side effect
  • Rash rare side effect
  • Cool, dry storage conditions
  • Second generation Cephalosporin therapeutic class

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