Forticef 1 gm/vial (IV Injection)

1 gm vial: ৳ 216.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Albion laboratories limited

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against Gram-positive and Gram-negative organisms
  • Interferes with synthesis of bacterial cell wall
  • High stability in the presence of beta lactamases
  • Long plasma elimination half-life of 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day or in equally divided doses twice a day
  • Maximum adult dose: 4 gm/day
  • Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day or in equally divided doses twice a day
  • Maximum pediatric dose: 2 gm/day
  • Duration of therapy: 4 to 14 days

Administration

  • Preparation of solutions for intramuscular/intravenous injections
  • Recommended injection concentration: 10 mg/mL to 40 mg/mL
  • Patient tolerance test recommended before starting treatment
  • Freshly reconstituted solution is recommended
  • Maintains potency for at least 6 hours at room temperature or 24 hours at 5°C

Interaction

  • No reported drug interactions

Contraindications

  • Patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects including diarrhea, nausea, vomiting, stomatitis, and glossitis
  • Cutaneous reactions including rash, pruritus, urticaria, edema, and erythema multiforme
  • Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia, anemia, and neutropenia
  • Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
  • CNS reactions including nervousness, confusion, sleep disturbances, headache, hyperactivity, convulsion, hypertonia, and dizziness
  • Local phlebitis occurs rarely following intravenous administration

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution in lactating mothers

Precautions & Warnings

  • Anaphylactic shock may occur
  • Shadows suggesting sludge in the gallbladder have been detected in rare cases
  • Blood picture should be checked during prolonged treatment

Use in Special Populations

  • Must not be given to premature and newborn neonates up to 28 days of age

Overdose Effects

  • No specific antidote
  • Treatment should be symptomatic

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C, away from light and moisture
  • Keep out of the reach of children

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