Forticef 1 gm/vial (IV Injection)
1 gm vial: ৳ 216.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Albion laboratories limited |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against Gram-positive and Gram-negative organisms
- Interferes with synthesis of bacterial cell wall
- High stability in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Highly protein bound (95%)
Dosage
- Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day or in equally divided doses twice a day
- Maximum adult dose: 4 gm/day
- Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day or in equally divided doses twice a day
- Maximum pediatric dose: 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Preparation of solutions for intramuscular/intravenous injections
- Recommended injection concentration: 10 mg/mL to 40 mg/mL
- Patient tolerance test recommended before starting treatment
- Freshly reconstituted solution is recommended
- Maintains potency for at least 6 hours at room temperature or 24 hours at 5°C
Interaction
- No reported drug interactions
Contraindications
- Patients with a history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastrointestinal effects including diarrhea, nausea, vomiting, stomatitis, and glossitis
- Cutaneous reactions including rash, pruritus, urticaria, edema, and erythema multiforme
- Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia, anemia, and neutropenia
- Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
- CNS reactions including nervousness, confusion, sleep disturbances, headache, hyperactivity, convulsion, hypertonia, and dizziness
- Local phlebitis occurs rarely following intravenous administration
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution in lactating mothers
Precautions & Warnings
- Anaphylactic shock may occur
- Shadows suggesting sludge in the gallbladder have been detected in rare cases
- Blood picture should be checked during prolonged treatment
Use in Special Populations
- Must not be given to premature and newborn neonates up to 28 days of age
Overdose Effects
- No specific antidote
- Treatment should be symptomatic
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place below 30°C, away from light and moisture
- Keep out of the reach of children