Itramax 100 mg (Capsule)

Unit Price: ৳ 15.00 (6 x 4: ৳ 360.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Itraconazole
Company Albion laboratories limited

Title

  • Itramax 100 mg Capsule

Categories

  • Antifungal Medication
  • Pharmaceuticals
  • Medication
  • Healthcare

Description

  • Itramax is used for the treatment of oropharyngeal candidiasis, vulvovaginal candidiasis, pityriasis versicolor, tinea pedis, tinea cruris, tinea corporis, tinea manuum, onychomycosis, histoplasmosis.
  • Indicated in the treatment of systemic candidiasis, aspergillosis, and cryptococcosis.
  • Maintenance therapy in AIDS patients to prevent relapse of underlying fungal infections.
  • Prevention of fungal infection during prolonged neutropenia.

Dosage & Administration

  • Dosage available in 100 mg, 130 mg, and 200 mg preparations.
  • Specific dosage for various fungal diseases such as vulvovaginal candidiasis, pityriasis versicolor, tinea corporis, tinea cruris, tinea pedis, tinea manuum, oropharyngeal candidiasis, onychomycosis, aspergillosis, candidiasis, non-meningeal cryptococcosis, cryptococcal meningitis, histoplasmosis, maintenance in AIDS, and prophylaxis in neutropenia.
  • Dose and duration of treatment should be adjusted depending on the clinical response.

Pharmacology

  • Inhibits Cytochrome P-450 dependent enzymes leading to impairment of ergosterol biosynthesis in yeast and fungal cells.
  • Utilizes SUBA (Super Bio-available) technology for enhancing bioavailability of poorly soluble drugs.

Interaction

  • Drugs like terfenadine, astemizole, cisapride, HMG-CoA reductase inhibitors such as simvastatin, oral midazolam or triazolam should not be given concurrently with Itramax.
  • Significant interactions observed during co-administration of rifampin, phenytoin, phenobarbital, digoxin, and calcium channel blockers.

Contraindications

  • Contraindicated in patients with known hypersensitivity to the drug or any ingredient in the formulation.
  • Patients with severe hepatic disease are not advised to take Itraconazole.
  • Not advisable to use the drug in patients taking rifampin.

Side Effects

  • Nausea, abdominal pain, dyspepsia, constipation, headache, dizziness, raised liver enzymes, menstrual disorders, allergic reactions, hepatitis and cholestatic jaundice, peripheral neuropathy, Stevens-Johnson syndrome, hypokalaemia, oedema, hair loss.

Pregnancy & Lactation

  • Contraindicated in pregnancy.
  • Breastfeeding while receiving Itraconazole is not recommended.

Precautions & Warnings

  • Absorption is impaired when gastric acidity is reduced.
  • Recommended to administer the drug after a full meal.
  • Rare cases of hepatitis and jaundice reported mainly in patients treated for longer than one month, therefore advised to monitor liver function in patients receiving continuous treatment of more than one month.

Therapeutic Class

  • Drugs for subcutaneous and mycoses

Storage Conditions

  • Store below 25°C, in a cool & dry place.
  • Keep away from light.
  • Keep all the medicine out of the reach of children.

Common Questions

  • What is Itramax 100 mg Capsule?
  • What is Itramax 100 mg Capsule used for?
  • Duration of effect?
  • Onset of action?
  • Pregnancy warnings?
  • Habit forming?
  • Breastfeeding warnings?

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