Aripra 5 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 75.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Aripiprazole |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title
- Aripra
Categories
- Neuroleptic Drugs
- Antipsychotic Medication
Description
- Aripiprazole medication for schizophrenia, bipolar disorder, major depressive disorder, autism, and agitation
Indications
- Schizophrenia
- Bipolar disorder
- Adjunctive treatment of major depressive disorder
- Irritability associated with autistic disorder
- Agitation associated with schizophrenia or bipolar mania
Pharmacology
- Atypical antipsychotic
- Partial agonist activity at Dopamine D2 and Serotonin 5-HT 1A receptors
- Antagonist activity at Serotonin 5-HT 2A receptors
Dosage
- Initial Dose: 10-15 mg/day for adults with schizophrenia
- Initial Dose: 2 mg/day for adolescents with schizophrenia
- Initial Dose: 15 mg/day for adults with bipolar mania (monotherapy)
- Initial Dose: 10-15 mg/day for adults with bipolar mania (adjunctive therapy)
- Initial Dose: 2-5 mg/day for adults with major depressive disorder
- Initial Dose: 2 mg/day for pediatric patients with irritability associated with autistic disorder
Mode of Administration
- Oral formulations - Administer once daily without regard to meals
- IM injection - Wait at least 2 hours between doses. Maximum daily dose 30 mg
Interaction
- Caution with centrally acting drugs and alcohol
- Carbamazepine interaction
- Inhibition of elimination by ketoconazole, quinidine, fluoxetine or paroxetine
Contraindications
- Known hypersensitivity to Aripiprazole
Side Effects
- Vomiting
- Nausea
- Akathisia
- Extrapyramidal disorder
- Somnolence
- Sedation
- Dizziness
- Insomnia
- Tremor
- Restlessness
- Fatigue
- Blurred vision
- Salivary hypersecretion
- Constipation
- Pyrexia
- Drooling
- Decreased appetite
Pregnancy & Lactation
- Pregnancy category C
- Avoid during pregnancy
- Not recommended for breastfeeding women
Precautions & Warnings
- Increased incidence of cerebrovascular adverse events in elderly patients with dementia-related psychosis
- Increased risk of suicidality with antidepressants
- Tardive dyskinesia - Discontinue if clinically appropriate
- Metabolic changes including hyperglycemia/diabetes mellitus, dyslipidemia, and body weight gain
- Use with caution in patients with known cardiovascular or cerebrovascular disease
- Use caution in patients with a history of seizures
- Caution when operating machinery
Overdose Effects
- No fatalities at doses up to 1080 mg
- Signs and symptoms: nausea, vomiting, asthenia, diarrhea, somnolence
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children