Dentro 25 mg (Capsule)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Dantrolene sodium
Company Healthcare pharmaceuticals ltd
Also available as

Indications

  • Chronic spasticity control
  • Manifestations of clinical spasticity
  • Upper motor neuronal disorders
  • Spinal cord injury
  • Stroke
  • Cerebral palsy
  • Multiple sclerosis
  • Functional rehabilitation
  • Reversible spasticity relief
  • Malignant hyperthermia prevention
  • Anesthesia
  • Surgery

Pharmacology

  • Relaxation of skeletal muscle
  • Affects contractile response
  • Site beyond myoneural junction
  • Interference with Ca++ release

Dosage & Administration

  • Gradual titration schedule
  • Maximum accepted dosage
  • Paediatric dosage schedule
  • Preoperative administration
  • Post-crisis follow-up

Interactions

  • Drowsiness
  • CNS depressants
  • Hepatotoxicity
  • Concomitant estrogen therapy

Contraindications

  • Active hepatic disease
  • Hepatitis
  • Cirrhosis

Side Effects

  • Drowsiness
  • Dizziness
  • Weakness
  • General malaise
  • Fatigue
  • Diarrhea
  • Transient side effects

Pregnancy & Lactation

  • Pregnancy Category C
  • Risk-benefit consideration
  • Avoidance in nursing mothers

Precautions & Warnings

  • Liver damage potential
  • 45-day efficacy assessment
  • Driving caution
  • Tranquilizing agents
  • Photosensitivity reaction
  • Liver function studies
  • Idiosyncratic liver disorders
  • Baseline liver function studies
  • Pulmonary function caution
  • Cardiac function caution
  • Females over 35 caution
  • History of liver disease caution

Use in Special Populations

  • Paediatric patients
  • Long-term safety considerations
  • Adverse effects monitoring

Therapeutic Class

  • Centrally acting Skeletal Muscle Relaxants

Storage Conditions

  • Cool & dry place
  • Protected from light

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