Mopride 2 mg (Tablet)
Unit Price: ৳ 24.00 (1 x 15: ৳ 360.00)
Strip Price: ৳ 360.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Prucalopride succinate |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Symptomatic treatment of chronic constipation in adults
Pharmacology
- Selective stimulator of the 5-HT4 receptors
- Stimulates motility in the gastrointestinal tract
- Produces the release of acetylcholine
Dosage & Administration
- Adults: 2 mg once daily with or without food
- Start with 1 mg once daily for older people
- Not recommended for children and adolescents under 18 years
Interaction
- Low interaction potential with other medicinal products
- Small increase in systemic exposure with potent CYP3A4 inhibitors like ketoconazole
- No clinically relevant effects on warfarin, digoxin, alcohol, paroxetine, or oral contraceptives
Contraindications
- Hypersensitivity to active substance or excipients
- Renal impairment requiring dialysis
Side Effects
- Most frequently reported adverse reactions: headache and gastrointestinal symptoms
- Adverse reactions occur predominantly at the start of therapy and usually disappear within a few days
Pregnancy & Lactation
- Not recommended during pregnancy
- Effective contraception should be used by women of childbearing potential during treatment
- Not recommended during breastfeeding
Precautions & Warnings
- Dose adjustment for severe renal impairment
- Caution in prescribing to patients with severe hepatic impairment
- Possible reduction in efficacy of oral contraceptives in case of severe diarrhea
- Not suitable for patients with rare hereditary problems of galactose intolerance
Use in Special Populations
- Dose adjustment for patients with severe renal impairment and severe hepatic impairment
Overdose Effects
- May result in symptoms like headache, nausea, and diarrhea
- Treated symptomatically and supportive measures instituted as required
Therapeutic Class
- Osmotic purgatives
Storage Conditions
- Store at room temperature below 30°C
- Dispense in original bottle