Fenocol 200 mg (Capsule)
Unit Price: ৳ 7.00 (30's pack: ৳ 210.00)
Medicine Details
Category | Details |
---|---|
Generic | Fenofibrate |
Company | Peoples pharma ltd |
Indications
- For hyperlipidemias of type lla, llb, III, IV & V
Pharmacology
- Fenofibrate is a fibric acid derivative
- Reduces total cholesterol, LDL cholesterol, Apo-lipoprotein B, Total triglycerides and VLDL
- Increases HDL and apo-proteins apoAI apoAII
- Reduces serum uric acid levels
- Enhanced absorption in micronised form
Dosage & Administration
- Initial dose for hypercholesterolemia is 200 mg per day
- Initial dose for hypertriglyceridemia is 67 to 200 mg per day
- Dose should be individualized according to patient response
- Should be given with meal to optimize bioavailability
Interaction
- Potentiates anticoagulant effects of warfarin
- May improve glucose tolerance
- May increase nephrotoxicity of cyclosporine
- Cautions with HMG-CoA reductase inhibitors
- Well tolerated with low-dose statins
Contraindications
- Hypersensitivity to Fenofibrate
- Severe renal or hepatic impairment
- Existing gall bladder disease
- Breast feeding mothers
- Photosensitivity to ketoprofen
Side Effects
- Gastro-intestinal issues
- Pruritus
- Urticaria
- Impotence
- Headache
- Dizziness
- Vertigo
- Fatigue
- Hair loss
- Myotoxicity
Pregnancy & Lactation
- Not recommended for pregnant women
Precautions & Warnings
- Special care needed in patients with renal disease
- Discontinue if myotoxicity suspected
- Liver function tests recommended every 3 months for first year
Overdose Effects
- No specific treatment for overdose
- General supportive care indicated
- Hemodialysis not recommended due to high protein binding
Therapeutic Class
- Fibrates
Storage Conditions
- Do not store above 30°C
- Keep away from light and out of the reach of children