Belsar-M 5 mg+40 mg (Tablet)

Unit Price: ৳ 20.00 (4 x 7: ৳ 560.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Amlodipine besilate olmesartan medoxomil
Company Beacon pharmaceuticals plc
Also available as
Belsar m 5 mg tablet

Title and Categories

  • Belsar-M Combination Drug
  • Antihypertensive
  • Calcium Channel Blocker
  • Angiotensin II Receptor Antagonist
  • Hypertension Treatment

Indications

  • Treatment of hypertension
  • Lowering blood pressure
  • Initial therapy for patients likely to need multiple antihypertensive agents

Pharmacology

  • Amlodipine as dihydropyridine calcium channel blocker
  • Greater effect on vascular smooth muscle cells
  • Peripheral arterial vasodilator
  • Olmesartan Medoxomil blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II
  • Selective blocking of AT1 receptor

Dosage and Administration

  • Titration of components for individual patients
  • Initial therapy with 5/20 mg once daily
  • Maximum dosage of 10/40 mg once daily

Interaction

  • Potential attenuation by NSAIDs including selective COX-2 inhibitors
  • Monitoring of blood pressure, renal function, and electrolytes

Contraindications

  • Incompatibility with co-administration of Aliskiren in patients with diabetes

Side Effects

  • Peripheral edema
  • Headache
  • Flushing
  • Dizziness
  • Sprue-like enteropathy

Pregnancy and Lactation

  • Pregnancy Category D
  • Avoidance in 2nd and 3rd trimester
  • Potential fetal death
  • Discontinuation during pregnancy or nursing if adverse effects are observed

Precautions and Warnings

  • Caution in volume- or salt-depleted patients
  • Risk in patients with severe aortic stenosis or obstructive coronary artery disease

Use in Special Populations

  • Lack of established safety and effectiveness in pediatric patients
  • No overall differences observed between subjects 65 years or older and younger subjects
  • No studies in patients with renal impairment
  • Initial therapy not recommended in hepatically impaired patients

Overdose Effects

  • No information available on humans

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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