Emixef 400 mg (Tablet)

Unit Price: ৳ 50.00 (2 x 4: ৳ 400.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Incepta pharmaceuticals ltd
Also available as
Emixef 200 mg capsule Emixef 400 mg capsule Emixef 100 mg suspension Emixef ds 200 mg suspension Emixef 25 mg pediatric drop Emixef 200 mg tablet

Indications

  • Treatment for Upper Respiratory Tract Infections (URTI)
  • Treatment for Lower Respiratory Tract Infections
  • Treatment for Urinary Tract Infections
  • Clinical efficacy against Streptococcus pneumoniae
  • Clinical efficacy against Escherichia coli
  • Orally active cephalosporin antibiotic
  • Bactericidal activity against Gram-positive organisms
  • Bactericidal activity against Gram-negative organisms
  • Marked in-vitro bactericidal activity
  • Highly stable in the presence of beta-lactamase enzymes

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against a broad spectrum of bacteria
  • Interferes with bacterial cell wall synthesis
  • Highly stable in the presence of Beta-lactamase enzyme
  • Absorption about 40% to 50% whether administered with or without food

Dosage & administration

  • Usual course of treatment is 7 days
  • Recommended adult dosage is 200-400 mg daily
  • Dosage for children over 10 years is same as adult dosage
  • Dosage for children aged less than 6 months has not been established
  • Dosage may be continued for up to 14 days if required

Interaction

  • Increases in prothrombin times noted in a few patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Known hypersensitivity to cephalosporin antibiotics

Side effects

  • Gastrointestinal disturbances like diarrhea and stool changes
  • Nausea, abdominal pain, dyspepsia, vomiting and flatulence
  • Headache and dizziness
  • Allergies in the form of rash, pruritus, urticaria
  • Thrombocytopenia, leukopenia and eosinophilia
  • Mild transient change in liver and renal function tests
  • Pseudomembraneous colitis has been reported

Pregnancy & lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Use with caution when administered to a nursing woman

Precautions & warnings

  • Given with caution to patients with known hypersensitivity to other drugs
  • Given with caution to penicillin-sensitive patients
  • Administered with caution in patients with markedly impaired renal function
  • Treatment alters the normal flora of the colon

Overdose effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Adverse reactions in healthy adult volunteers receiving single doses up to 2 g

Therapeutic class

  • Third generation Cephalosporins

Storage conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical structure

  • Molecular Formula: C16H15N5O7S2

Common questions about Emixef 400 mg Tablet

  • Emixef 400 mg Tablet used to treat bacterial infection
  • Uses include Urinary Tract Infection, Tonsillitis, Pharyngitis, Bronchitis
  • Reported side effects include Diarrhea, Abdominal pain, Dizziness

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