Rapilog 100 IU/ml (SC Injection)

Indications

• Indicated to improve glycemic control in adults and children with diabetes mellitus

Composition

• Each ml suspension contains 100 IU (equivalent to 3.50 mg) Insulin Aspart (rDNA) BP as 30% soluble Insulin Aspart and 70% protamine-crystallised Insulin Aspart

Description

• Sterile suspension of human insulin analog containing 30% soluble Rapilog and 70% protamine-crystallised Rapilog
• Blood glucose lowering agent with earlier onset and intermediate duration of action

Pharmacology

• Regulates glucose metabolism by binding to insulin receptors on muscle and fat cells

Dosage

• Individual and determined by the physician according to patient's needs
• Can be given in mono-therapy or in combination with oral antidiabetic drugs
• Recommended starting dose for type 2 diabetes
• Dose adjustments can be made once a week until target HbA1c is reached
• Usual insulin requirement for type 1 diabetes is between 0.5 and 1.0 IU/kg/day

Administration

• Administer 5-10 min before meal

Interaction

• Some drugs may require dose adjustment when used with Insulin Aspart

Contraindications

• Contraindicated during episodes of hypoglycemia
• In patients with hypersensitivity to Insulin Aspart or its excipients

Side Effects

• Hypoglycemia
• Allergic reactions
• Injection site reaction
• Lipodystrophy
• Pruritus
• Rash

Pregnancy & Lactation

• Pregnancy category B
• No restrictions on treatment during lactation, but dosage may need to be adjusted

Precautions & Warnings

• Blood glucose should be monitored in all patients treated with insulin
• Dosage adjustment and monitoring should be done cautiously under medical supervision

Use in Special Populations

• Decreased dose may be necessary in patients with renal impairment
• Decreased dose may be necessary in patients with hepatic impairment

Overdose Effects

• Hypoglycemia may develop over sequential stages if too high doses are administered
• Mild hypoglycemic episodes can be treated by oral administration of glucose or sugary products
• Severe hypoglycemic episodes can be treated by glucagon given intramuscularly or subcutaneously

Therapeutic Class

• Rapid Acting Insulin

Storage Conditions

• Store at 2°C to 8°C in a refrigerator
• Do not freeze
• Protect from light

Related Brands

• Glyset Mix 100 IU/ml (SC Injection) - incepta-pharmaceuticals-ltd