Pirfedone 534 mg (Tablet)

Unit Price: ৳ 80.00 (3 x 6: ৳ 1,440.00)
Strip Price: ৳ 480.00

Medicine Details

Category Details
Generic Pirfenidone
Company Renata limited
Also available as
Pirfedone 267 mg tablet Pirfedone 801 mg tablet

Indications

  • Treatment of mild to moderate Idiopathic Pulmonary Fibrosis (IPF)

Pharmacology

  • Anti-inflammatory properties
  • Antioxidant properties
  • Anti-fibrotic properties
  • Improvement of lung function
  • Reduction of acute exacerbations in patients with IPF
  • Suppression of TGF-β1
  • Downregulation of pro-inflammatory cytokines

Dosage & Administration

  • Route of administration: Oral with food
  • Initial titration dose
  • Recommended daily dose of 2403 mg/day
  • Dose adjustments for gastrointestinal events
  • Dose adjustments for photosensitivity reaction or rash
  • Dose adjustments for hepatic function
  • Treatment interruption guidelines

Interaction

  • Moderate and strong CYP1A2 inhibitors
  • Impact of food on adverse reactions

Contraindications

  • Hypersensitivity to active substance or excipients
  • Concomitant use of fluvoxamine
  • Severe hepatic impairment or end-stage liver disease
  • Severe renal impairment
  • End-stage renal disease requiring dialysis

Side Effects

  • Common side effects
  • Rare side effects

Pregnancy & Lactation

  • Pregnancy precautions
  • Lactation precautions
  • Fertility effects

Precautions & Warnings

  • Elevated liver enzymes
  • Photosensitivity and rash
  • Gastrointestinal disorders

Use in Special Populations

  • Use in Children & Adolescents
  • Hepatic Impairment
  • Renal Impairment
  • Smokers' altered exposure

Overdose Effects

  • Limited clinical overdose experience

Therapeutic Class

  • Immunosuppressant

Storage Conditions

  • Cool and dry storage
  • Protection from light and moisture
  • Keep out of reach of children

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