Pulmobi 267 mg (Tablet)

Unit Price: ৳ 45.00 (3 x 10: ৳ 1,350.00)

Strip Price: ৳ 450.00

Medicine Details

Category	Details
Generic	Pirfenidone
Company	Biopharma limited
Also available as	Pulmobi 801 mg tablet Pulmobi 534 mg tablet

Title and Category

Pulmobi
Medicine
Immunosuppressant

Indications

Treatment of mild to moderate Idiopathic Pulmonary Fibrosis (IPF)

Pharmacology

Anti-inflammatory
Antioxidant
Anti-fibrotic properties
Improves lung function
Reduces acute exacerbations
Suppresses TGF-β1
Downregulates pro-inflammatory cytokines

Dosage & Administration

Oral administration with food
Initial titration period
Recommended daily dose of tablets
Dose adjustments for gastrointestinal events and photosensitivity reaction or rash
Hepatic function monitoring

Interaction

Modulation by moderate and strong inhibitors of CYP1A2
Impact of food on adverse reactions

Contraindications

Hypersensitivity to active substance or excipients
Concomitant use of fluvoxamine
Severe hepatic or renal impairment

Side Effects

Common: nausea, rash, abdominal pain, upper respiratory tract infection
Rare: photosensitivity reaction, decreased appetite, pruritus

Pregnancy & Lactation

Precautionary avoidance during pregnancy
Unknown excretion in human milk
No effects on fertility and reproductive performance in rats

Precautions & Warnings

Monitoring of liver enzymes
Avoidance of sunlight and sunlamps
Monitoring and management of gastrointestinal disorders

Use in Special Populations

Safety and effectiveness in children & adolescents unknown
Monitoring and dosage modification in hepatic and renal impairment
Altered exposure in smokers

Overdose Effects

Limited clinical experience
Mild, transient adverse reactions observed with escalated doses

Therapeutic Class

Immunosuppressant

Storage Conditions

Cool, dry place
Protection from light & moisture
Keep out of reach of children

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