Itra 200 mg (Tablet)

Unit Price: ৳ 28.00 (3 x 6: ৳ 504.00)
Strip Price: ৳ 168.00

Medicine Details

Title

  • Itra 200 mg Tablet

Categories

  • Medicine
  • Antifungal Medication
  • Therapeutic Drugs

Description

  • Itraconazole inhibits Cytochrome P-450 dependent enzymes resulting in impairment of the biosynthesis of ergosterol, a major component of the cell membrane of yeast and fungal cells.
  • SUBA (Super Bio-available) technology is a novel technology for enhancing the bioavailability of poorly soluble drugs.

Indications

  • Oropharyngeal candidiasis
  • Vulvovaginal candidiasis
  • Pityriasis versicolor
  • Tinea pedis
  • Tinea cruris
  • Tinea corporis
  • Tinea manuum
  • Onychomycosis
  • Histoplasmosis
  • Systemic candidiasis
  • Aspergillosis
  • Cryptococcosis

Pharmacology

  • Inhibition of ergosterol biosynthesis
  • Cell membrane abnormalities
  • Permeability alterations
  • Chitin synthesis inhibition
  • Abnormal cell wall formation
  • Intracellular lipids accumulation
  • Membranous vesicles accumulation
  • SUBA technology for bioavailability enhancement

Dosage & Administration

  • 100 mg & 200 mg preparation
  • 65 mg & 130 mg preparation
  • Non-systemic fungal disease dosages
  • Systemic fungal disease dosages
  • Pediatric use precautions
  • Dose adjustment based on clinical response

Interaction

  • Drugs contraindicated for concurrent use
  • Significant interactions observed with specific medications
  • No experience of overdosage

Contraindications

  • Hypersensitivity to the drug or any ingredient
  • Severe hepatic disease
  • Concurrent use with rifampin

Side Effects

  • Nausea
  • Abdominal pain
  • Dyspepsia
  • Headache
  • Dizziness
  • Raised liver enzymes
  • Menstrual disorders
  • Allergic reactions
  • Hepatitis
  • Cholestatic jaundice
  • Peripheral neuropathy
  • Stevens-Johnson syndrome
  • Hypokalaemia
  • Oedema
  • Hair loss

Pregnancy & Lactation

  • Contraindicated in pregnancy
  • Not recommended for breastfeeding

Precautions & Warnings

  • Impaired absorption with reduced gastric acidity
  • Administration with acid neutralizing medicines
  • Administration after a full meal
  • Monitoring of liver function for prolonged treatment
  • Cases of hepatitis and jaundice reported

Therapeutic Class

  • Drugs for subcutaneous and mycoses

Storage Conditions

  • Store below 25°C
  • Cool & dry place
  • Keep away from light
  • Keep out of reach of children

Commonly Asked Questions

  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Breastfeeding warnings
  • Habit forming status
  • Quick tips for usage

Usability

  • Helps treat fungal infections
  • Reliable contraception advice
  • Monitoring of liver function
  • Importance of completing full course of treatment

Technology

  • SUBA technology for bioavailability enhancement

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