Calnor 10 mg+20 mg (Tablet)
Unit Price: ৳ 15.00 (2 x 14: ৳ 420.00)
Strip Price: ৳ 210.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of hypertension alone or with other antihypertensive agents
- Lowering blood pressure
- Initial therapy in patients likely to need multiple antihypertensive agents
- Individualized blood pressure goals
Pharmacology
- Amlodipine - dihydropyridine calcium channel blocker
- Greater effect on vascular smooth muscle cells
- Peripheral arterial vasodilator
- Olmesartan Medoxomil - selective blocker of AT1 receptor
- Blockage of vasoconstrictor and aldosterone-secreting effects of angiotensin II
Dosage & Administration
- Substitute individually titrated components
- Initial therapy with 5/20 mg once daily
- Titration up to a maximum of 10/40 mg once daily
- Reduced starting dose of Amlodipine for elderly patients
Interaction
- Possible attenuation by NSAIDs including selective COX-2 inhibitors
- Close monitoring of blood pressure, renal function, and electrolytes
Contraindications
- Co-administration with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Avoid use in 2nd and 3rd trimester
- Discontinue if pregnancy is detected
- Potential adverse effects on nursing infant
Precautions & Warnings
- Caution in volume- or salt-depleted patients
- Vasodilation in patients with severe aortic stenosis
- Increased frequency, duration, or severity of angina or acute MI in patients with severe obstructive coronary artery disease
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety or effectiveness in geriatric use
- No studies in patients with renal impairment
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- No information available for overdose in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of reach of children