Tergocin 400 mg/vial (IM/IV Injection)

400 mg vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Teicoplanin
Company Incepta pharmaceuticals ltd
Also available as
Tergocin 200 mg injection

Indications

  • Complicated skin and soft tissue infections
  • Bone and joint infections
  • Hospital-acquired pneumonia
  • Community-acquired pneumonia
  • Complicated urinary tract infections
  • Infective endocarditis
  • Clostridium difficile infection-associated diarrhea
  • Alternative oral treatment for Clostridium difficile infection-associated diarrhea and colitis

Pharmacology

  • Teicoplanin is a glycopeptide-antibiotic
  • Produced by Actinoplanes teichomyceticus
  • Interferes with cell-wall biosynthesis
  • Inhibits the growth of susceptible organisms
  • Blocks peptidoglycan synthesis

Dosage & Administration

  • Intravenous administration
  • Intramuscular administration
  • Bolus injection
  • Infusion method
  • Once daily dosing
  • Loading doses
  • Maintenance doses
  • Dosage adjustment based on infection severity and patient response
  • Adaptation for adults, elderly, and children
  • Treatment duration based on infection severity
  • Administration for Clostridium difficile infection-associated diarrhea

Interaction

  • Co-administration caution with nephrotoxic drugs
  • Co-administration caution with ototoxic drugs
  • Caution with Aminoglycosides
  • Caution with Amphotericin B
  • Caution with Cyclosporion
  • Caution with Frusemide

Contraindications

  • Hypersensitivity to teicoplanin

Side Effects

  • Local reaction - Erythema, injection site abscess
  • Allergic reaction - Rash, pruritus, fever, anaphylactic reactions
  • Gastrointestinal reactions - Nausea, vomiting, diarrhea
  • CNS reactions - Physical weakness, dizziness, headache
  • Hearing reactions - Ringing in the ears, balance disorders

Pregnancy & Lactation

  • Pregnancy Category B3
  • Not recommended during confirmed or presumed pregnancy
  • Not recommended during lactation unless benefits outweigh risks

Precautions & Warnings

  • Caution in patients known to be hypersensitive to Vancomycin
  • Potential cross-hypersensitivity with Vancomycin

Therapeutic Class

  • Glycopeptide antibiotic

Reconstitution

  • Slow injection of water for reconstitution
  • Rotating vial to dissolve powder
  • Prevention of foaming during reconstitution
  • Use of specific infusion solutions

Storage Conditions

  • Temperature not exceeding 30°C
  • Dry place storage
  • Protection from light
  • Immediate use of reconstituted solution
  • Refrigerated storage for reconstituted solution

Related Brands