Pico 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Sodium picosulfate |
| Company | Chemist laboratories ltd |
| Also available as |
Indications
- Constipation of any etiology
- Relief from prolonged & recurrent constipation
- Bowel clearance before surgery, childbirth or radiological investigations.
Pharmacology
Sodium Picosulfate is a triarylmethane group derivative stimulant laxative. It is activated by the colonic bacteria and acts locally in the colon, stimulating nerve endings of the intestinal wall and promoting accumulation of water and electrolytes resulting in colonic peristalsis, reduction of transit time, and softening of the stool.
Dosage & Administration
- 10 mg tablet dose:
- Adults and children over 10 years of age: 5-10 mg per day
- Children aged 4-10 years: 2.5-5 mg per day
- Oral Solution (5 mg/5 ml) dose:
- Adults and children over 10 years of age: 5-10 ml or one to two teaspoonful per day
- Children aged 4-10 years: 2.5-5 ml or half to one teaspoonful per day
- Children from One month to 4 years of age: 0.25 ml/kg body weight per day
- Concentrated Oral Solution (7.5 mg/ml) dose:
- Adults and children over 10 years of age: 0.67-1.33 ml per day
- Children aged 4-10 years: 0.33-0.67 ml per day
Interaction
Concomitant use of diuretics or adreno-corticosteroids may increase risk of electrolyte imbalance. Concurrent administration of antibiotics may reduce the laxative action of Pico.
Contraindications
- Ileus or intestinal obstruction
- Severe painful and/or feverish acute abdominal conditions (e.g. appendicitis)
- Acute inflammatory bowel diseases
- Severe dehydration
- Known hypersensitivity to Sodium Picosulfate or any other component of the product
Side Effects
- Hypersensitivity
- Dizziness
- Syncope
- Gastrointestinal disorders
- Diarrhea
- Abdominal pain and cramps
- Nausea
- Vomiting
Pregnancy & Lactation
No reports of undesirable effects during pregnancy or to the foetus attributable to the use of this product. Use of the drug should be avoided during the first trimester. Clinical data show that neither the active moiety of sodium Picosulfate nor its glucuronides are excreted into the milk of healthy lactating females.
Precautions & Warnings
Prolonged excessive use may lead to fluid and electrolyte imbalance and hypokalemia. Harmful for those suffering from alcoholism. To be taken into account in pregnant or breastfeeding women, children, and high-risk groups such as patients with liver disease or epilepsy.
Overdose Effects
Laxatives when taken in chronic overdosage may cause chronic diarrhea, abdominal pain, hypokalemia, secondary hyperaldosteronism, renal calculi, renal tubular damage, metabolic alkalosis, and muscle weakness secondary to hypokalemia.
Therapeutic Class
Stimulant Laxative
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C18H15NNa2O9S2
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-1480-sodium-picosulfate-chemical-structure-VXribBHk7yHHQxt7umhH.svg
Common Questions about Pico 10 mg Tablet
- What is Pico 10 mg Tablet?: Pico 10 mg Tablet belongs to the class of laxatives.
- What are the uses of the Pico 10 mg Tablet?: Pico 10 mg Tablet is used in the treatment of constipation.
- How long do I need to use Pico 10 mg Tablet before I see improvement in my condition?: Pico 10 mg Tablet is to be taken till the time you see an improvement in your health conditions.
- At what frequency do I need to use Pico 10 mg Tablet?: Pico 10 mg Tablet should be taken in the dosage as prescribed by the doctor.
- Should I use Pico 10 mg Tablet empty stomach, before food or after food?: Pico 10 mg Tablet should be taken at bed-time as it requires 6-8 hours to show effect.
- What are the instructions for the storage and disposal of Pico 10 mg Tablet?: Pico 10 mg Tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.
- Is Pico 10 mg Tablet safe for pregnant women?: Pico 10 mg Tablet is not prescribed to pregnant women unless necessary. Consult your doctor beforehand.
- Is Pico 10 mg Tablet safe for breastfeeding women?: Breastfeeding women are not suggested to take Pico 10 mg Tablet unless necessary. Consult your doctor beforehand.
- Is Pico 10 mg Tablet a habit forming drug?: No case of addiction has been reported yet.
- What if I miss a dose of Pico 10 mg Tablet?: Take Pico 10 mg Tablet as soon as you remember. However, stick to your routine if it's the time for the next dose. Do not double the dose.
- Quick Tips:
- Together with Pico 10 mg Tablet, taking a fiber-rich diet containing whole grain bread and cereals, bran, fruits and green leafy vegetables, is essential to maintain healthy bowel function.
- Avoid taking a Pico 10 mg Tablet for more than 1 week, unless prescribed by the doctor, as it leads to dependency on the laxative action to produce a bowel movement.
- Take Pico 10 mg Tablet after 2 hours from other medicines, as it may interfere with the absorption of other medicines.
- Pico 10 mg Tablet should be preferably taken at bedtime because it requires 6 to 8 hours to show impact.