Thyrox 75 mcg (Tablet)
Unit Price: ৳ 3.10 (1 x 60: ৳ 186.00)
Strip Price: ৳ 186.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levothyroxine sodium |
| Company | Renata limited |
| Also available as |
Indications
- Replacement therapy in hypothyroidism
- Suppression of Thyroid Stimulating Hormone levels
- Goitrogenic effects suppression
- Diagnostic aid in suppression tests
Pharmacology
- Contains synthetic Levothyroxine
- Identical to natural hormone T4
- Converted to more active Triiodothyronine in peripheral tissues
- Major carrier is TBG
- Long half-life in circulation
- Liver is major site of degradation
- Enterohepatic circulation
- Steady blood level of T3 obtained from single daily dose
Dosage & Administration
- Adult dose
- Pediatric dosage (Newborns)
- Pediatric dosage (Infants and Children)
- Dose adjustment based on clinical response and laboratory parameters
Interaction
- Concurrent use of tri/tetracyclic antidepressants
- Administration of sertraline
- Addition of Thyrox to antidiabetic or insulin therapy
- Reduced serum digitalis glycoside levels
Contraindications
- Untreated subclinical or overt Thyrotoxicosis
- Acute Myocardial Infarction
- Uncorrected Adrenal failure
Side Effects
- Fatigue
- Increased appetite
- Headache
- Tremors
- Palpitations
- Diarrhea
- Hair loss
Pregnancy & Lactation
- Pregnancy Category A
- Increased Levothyroxine requirements during pregnancy
- Caution during nursing
- Adequate replacement doses needed for normal lactation
Precautions & Warnings
- Adrenocortical insufficiency
- Careful dosing in cardiovascular disease and severe hypothyroidism
- Adjustment of dosage with marked change in body weight
- Monitoring blood levels of T3 and T4
- Serum level of TSH monitoring
- Intoxication with Thyroid preparations
Overdose Effects
- Signs and symptoms of overdose
- Treatment for overdose
Therapeutic Class
- Thyroid drugs & hormone
Storage Conditions
- Store below 30°C and dry place
- Protect from light
- Keep out of the reach of children