Alenil 10 mg/ml (IV Injection)
1 ml ampoule: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria and allergen induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Inhibition of histamine-mediated early phase of allergic reaction
- Reduction of migration of inflammatory cells and release of mediators associated with late phase of allergic reaction
- Peak plasma concentrations of 257 mcg/L within one hour of administration
Dosage & Administration
- Cetirizine oral dosage form for adults and children
- Cetirizine injectable dosage form for adults, adolescents, and children
- Single use injectable product for intravenous administration only
- Recommended dosage regimen for acute urticaria
- Not recommended in pediatric patients less than 6 years of age with impaired renal or hepatic function
Interaction
- No clinically significant drug interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin
Contraindications
- History of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Most common side effect is somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category of Cetirizine Hydrochloride is B
- No adequate and well-controlled studies in pregnant women
- Caution should be exercised when administered to a nursing woman
Precautions & Warnings
- Caution should be exercised when driving a car or operating heavy machinery
Use in Special Populations
- Total body clearance of Alenil is reduced and AUC and half-life increased in patients with mild to moderate hepatic and renal impairment
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Clearance of Alenil is reduced in elderly patients, but only in proportion to the decrease in creatinine clearance
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children