Avirax HC 5%+1% (Cream)

10 gm tube: ৳ 70.00

Medicine Details

Category Details
Generic Acyclovir hydrocortisone
Company Healthcare pharmaceuticals ltd

Indications

  • Early treatment of recurrent herpes labialis (cold sores)
  • Reduction of ulcerative cold sores likelihood
  • Shortening lesion healing time in adults and children

Pharmacology

  • Inhibitory activity against Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2)
  • Synthetic purine nucleoside analogue
  • Selective affinity for thymidine kinase (TK) enzyme
  • Conversion into Acyclovir monophosphate, a nucleotide analogue
  • Stops replication of herpes viral DNA

Dosage & Administration

  • Topical application 5 times per day for 5 days
  • Initiation of therapy as early as possible after the first signs and symptoms

Contraindications

  • No known contraindication

Side Effects

  • Local skin reactions like drying or flaking of the skin
  • Burning or tingling
  • Erythema
  • Pigmentation changes
  • Application site reactions including signs and symptoms of inflammation

Pregnancy & Lactation

  • Pregnancy Category B
  • No adequate and well-controlled studies of systemic Acyclovir in pregnant women
  • Minimal systemic exposure of Acyclovir and Hydrocortisone following topical administration
  • Caution needed when administered to a nursing woman

Precautions & Warnings

  • Not to be used in the eye, inside the mouth or nose, or on the genitals
  • Medical advice should be sought if a cold sore fails to heal within 2 weeks

Use in Special Populations

  • Safety and effectiveness not established in pediatric subjects less than 6 years of age

Therapeutic Class

  • Hydrocortisone
  • Combined preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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