Coralbest-DX 600 mg+400 IU (Tablet)

Indications

• Treatment & prevention of Osteoporosis
• Treatment & prevention of Osteomalacia
• Treatment & prevention of Tetany
• Treatment & prevention of Hypoparathyroidism
• Treatment & prevention of Disorders of osteogenesis
• Supplement for inadequate intake of Calcium in childhood diet
• Supplement for rickets
• Supplement for pregnancy & lactation
• Supplement for elderly patients
• Pancreatitis treatment
• Phosphate binder in chronic renal failure

Composition

• Each tablet contains Calcium Carbonate USP 1250 mg (Coral source) equivalent to 500 mg of elemental Calcium & Vitamin D USP 200 IU
• Each DX tablet contains Calcium Carbonate USP 1500 mg (Coral source) equivalent to 600 mg of elemental Calcium & Vitamin D USP 400 IU
• Each effervescent tablet contains Calcium Carbonate (Coral source) USP 1500 mg equivalent to 600 mg of elemental Calcium and Vitamin D3 400 IU as Cholecalciferol USP

Pharmacology

• Calcium is vital for bodily functions
• Calcium is useful for prevention and treatment of Osteoporosis
• Vitamin D aids in Calcium absorption and bone formation
• Synergistic effects of Calcium and Vitamin D on bone growth
• Coral Calcium sourced for better absorption
• Vitamin D3 helps maintain Calcium balance in the body

Dosage & Administration

• One tablet once or twice daily with water
• Effervescent tablet should be dissolved in water before drinking

Interactions

• Thiazide diuretics reduce urinary excretion of calcium
• Systemic corticosteroids reduce calcium absorption
• Ion exchange resins and laxatives may reduce vitamin D absorption
• Calcium carbonate may interfere with tetracycline absorption
• Hypercalcaemia increases toxicity of cardiac glycosides
• Combinations with bisphosphonates or sodium fluoride should be spaced apart
• Oxalic acid and phytic acid inhibit calcium absorption

Contraindications

• Hypercalcemia and hyperparathyroidism
• Hypercalciuria and nephrolithiasis
• Hypersensitivity to the components
• Severe renal insufficiency
• Concomitant digoxin therapy

Side Effects

• GI irritation
• Constipation
• Hypercalcemia
• Allergic reactions
• Irregular heartbeats
• Nausea
• Vomiting
• Decreased appetite
• Dry mouth
• Drowsiness
• Skin rash from Vitamin D supplements

Pregnancy & Lactation

• Recommended daily intake during pregnancy
• Avoid overdoses of calcium and vitamin D
• No evidence of teratogenicity in humans
• Caution in breastfeeding mothers
• Considerations for giving additional vitamin D to the child

Precautions & Warnings

• Monitor serum calcium levels during long-term treatment
• Monitor renal function in elderly patients
• Consideration for patients with impaired renal function
• Avoid soft tissue calcification
• Caution in patients with severe renal insufficiency
• Close monitoring for sarcoidosis patients
• Increased risk of hypercalcaemia in immobilized patients
• Caution in prescribing other drugs containing vitamin D

Overdose Effects

• Hypervitaminosis D and hypercalcemia
• Symptoms of hypercalcemia
• Treatment of hypercalcemia
• Monitoring serum electrolytes and renal function

Therapeutic Class

• Specific mineral & vitamin combined preparations

Storage Conditions

• Store below 30°C
• Protect from light & moisture
• Keep out of reach of children

Common Questions about Coralbest-DX 600 mg Tablet

• Prevention and treatment of calcium and vitamin D deficiency
• Prevention of osteoporosis
• Treatment of rickets
• Treatment of osteomalacia
• Improvement of bone health in the elderly
• People who should avoid taking the tablet
• Common side effects
• Dosage instructions
• Precautions for taking the tablet

Related Brands

• Coralbest-D 500 mg+200 IU (Tablet) - sharif-pharmaceuticals-ltd
• Corafast-DX 600 mg+400 IU (Tablet) - albion-laboratories-limited
• Corafast-D 500 mg+200 IU (Tablet) - albion-laboratories-limited
• Oscoral D 500 mg+200 IU (Tablet) - novatek-pharmaceuticals-ltd
• Oscoral DX 600 mg+400 IU (Tablet) - novatek-pharmaceuticals-ltd