Fexobest 120 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Fexofenadine hydrochloride
Company Goodman pharmaceuticals ltd
Also available as
Fexobest 180 mg tablet Fexobest 30 mg suspension

Title

Fexobest 120 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

Fexobest is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis and chronic idiopathic urticaria in adults and children 12 years of age and older.

Indications

  • Relief of symptoms associated with seasonal and perennial allergic rhinitis
  • Relief of symptoms associated with chronic idiopathic urticaria

Dosage and administration

  • Allergic rhinitis:
    • Adults and children 12 and older:
      • 60 mg twice daily
      • 120 mg once daily
      • 180 mg once daily
    • Children 6 to 11 years:
      • 30 mg twice daily
      • 60 mg once daily
    • Children 2 to 11 years:
      • 30 mg or 5 ml twice daily
  • Chronic idiopathic urticaria:
    • Adults and children 12 and older:
      • 60 mg twice daily
      • 120 mg once daily
      • 180 mg once daily
    • Children 6 to 11 years:
      • 30 mg twice daily
      • 60 mg once daily
    • Children 6 months to less than 2 years:
      • 15 mg or 2.5 ml (1/2 tsp) twice daily

Pharmacology

Fexofenadine is an H1 histamine receptor inverse agonist, preventing activation and downstream effects. It has potent and selective affinity for H1 receptors, without CNS effects.

Interaction

  • Erythromycin or ketoconazole: 2-3 times increase in fexofenadine level in plasma
  • Omeprazole: No interaction observed
  • Antacid containing aluminium and magnesium hydroxide: Reduction in bioavailability if administered 15 minutes prior to Fexobest

Contraindications

  • Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Side effects

  • Common:
    • Headache
    • Drowsiness
    • Dizziness
    • Nausea
  • Uncommon:
    • Fatigue
  • Post marketing surveillance:
    • Hypersensitivity reactions
    • Insomnia
    • Tachycardia
    • Diarrhea
    • Rash
    • Urticaria
    • Pruritus

Pregnancy and lactation

  • Not recommended for use in pregnancy or breastfeeding

Precautions and warnings

  • Older people and renally or hepatically impaired patients: Limited data available, should be administered with care
  • Patients with cardiovascular disease: Should be warned about potential adverse reactions
  • Ability to drive and use machines: Unlikely to produce effect on the ability to drive or use machines

Use in special populations

  • Renal and hepatic impaired patient: Altered pharmacokinetics in renal impairment, no substantial effect in moderate to severe hepatic disease
  • Elderly patient: Similar adverse events to patients under 65 years, altered pharmacokinetics in individuals over 65 years

Overdose effects

  • Reported effects:
    • Dizziness
    • Drowsiness
    • Fatigue
    • Dry mouth
  • Maximum tolerated dose: Not established
  • Treatment recommendation: Symptomatic and supportive treatment, haemodialysis does not effectively remove Fexobest from blood

Therapeutic class

Non-sedating antihistamines

Storage conditions

Keep in a dry place away from light and heat. Keep out of the reach of children

Chemical structure

  • Molecular formula: C32H39NO4
  • Chemical structure image: https://medex.com.bd/storage/res/g-res-468-fexofenadine-hydrochloride-chemical-structure-HrM3XW8ofnGVhLdcBRox.svg

Commonly asked questions

  • What is Fexobest 120: An antihistamine that blocks histamine during allergic reactions
  • Uses of Fexobest 120: Treatment of allergic rhinitis and urticaria
  • Side Effects of Fexobest 120:
    • Vomiting
    • Headache
    • Coughing
    • Diarrhea
    • Painful menstruation
    • Hives and redness of skin
    • Swelling of face, lips, eyelids, tongue, hands and feet
  • Storage and disposal instructions: Keep in a cool dry place and in its original pack. Ensure it remains unreachable to children and pets
  • Can Fexobest 120 make you sleepy: Yes, it can cause sleepiness
  • Can you overdose on Fexobest 120: Overdose can cause adverse reactions
  • How quickly does Fexobest 120 work: Starts working within 1 hour
  • Does Fexobest 120 relieve symptoms of outdoor and indoor allergies: Yes, it can help relieve symptoms caused by outdoor and indoor allergens
  • How to cope with dizziness caused by Fexobest 120: Take rest, avoid heavy machinery, and consult a doctor if extreme dizziness occurs
  • Can I take antacids while taking Fexobest 120: Should not be used in combination with antacids
  • How should I take Fexobest 120: As recommended by the doctor
  • Foods or drinks to avoid while taking Fexobest 120: Avoid juices like grapefruit, orange, and apple juice
  • Can Fexobest 120 cause heart problems: Exercise caution if suffering from heart disorders
  • Quick Tips:
    • An antihistaminic medication
    • Less likely to cause sleepiness
    • Do not take with fruit juices
    • May cause nausea
    • Avoid using with antacids

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