Mythrocin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Erythromycin oral
Company Goodman pharmaceuticals ltd

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Ear infections
  • Eye infections
  • Skin and Soft tissue infections
  • Gastrointestinal tract infections
  • Prophylaxis
  • Other infections

Categories

  • Antibiotic
  • Anti-infective
  • Macrolides
  • Medication

Description

Belongs to the macrolides group of antibiotics and exerts a bacteriostatic or bactericidal action based on specific interference with ribosomal protein synthesis within the bacterial cell.

Pharmacology

  • Mode of Action: Inhibits microsomal protein synthesis in susceptible organisms by inhibiting the translocation process
  • Specific Binding: to the 50S subunit or 70S ribosome
  • Activity: Against many Gram-positive bacteria, some Gram-negative bacteria, mycoplasmas, and chlamydia
  • Absorption: Diminished by the presence of food
  • Blood Concentration: Peak serum concentrations after an oral dose
  • Distribution: Widely distributed throughout body tissue and fluids with some retention in the liver and spleen
  • Excretion: 5 to 15% of the dose excreted in the urine

Dosage Administration

  • Adult Children Over 8 Years: 250-500 mg every six hours for mild to moderate infections
  • Elderly: No special dosage recommendation
  • Children Aged 2 to 8 Years: 250 mg every six hours or 30-50 mg/kg body weight per day
  • Infants Children Upto 2 Years: 500 mg in divided doses or 30-50 mg/kg body weight in divided doses

Interaction

Use in patients receiving high dosage of theophylline may be associated with an increase of serum theophylline levels and potential theophylline toxicity

Contraindications

Known hypersensitivity to Erythromycin

Side Effects

  • Allergic reactions
  • Abdominal discomfort
  • Nausea
  • Vomiting

Pregnancy Lactation

Erythromycin crosses the placental barrier and is excreted in breast milk

Precautions Warnings

Should be given with care in patients with impaired hepatic function

Overdose Effects

Discontinued in case of overdosage

Drug Classes

  • Anti-diarrhoeal
  • Antimicrobial drugs
  • Macrolides

Reconstitution

Direction for reconstitution of suspension provided

Storage Conditions

Keep below 25°C temperature, away from light & moisture, out of the reach of children

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