Omehil 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Omeprazole
Company Goodman pharmaceuticals ltd
Also available as
Omehil 40 mg capsule

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Benign gastric and duodenal ulcer: 20 mg once daily for 4 weeks
  • NSAID-associated duodenal or gastric ulcer: 20 mg once daily for 4 weeks
  • Gastro-esophageal reflux disease: 20 mg once daily for 4 weeks
  • Long-term management of acid reflux disease: 10-20 mg daily
  • Acid-related dyspepsia: 10-20 mg once daily for 2-4 weeks
  • Prophylaxis of acid aspiration: 40 mg on the preceding evening, then 40 mg 2-6 hours before surgery
  • Zollinger- Ellison syndrome: Initial dose of 60 mg once daily
  • Helicobacter pylori eradication regimen in peptic ulcer disease: 20 mg twice daily
  • Paediatric use in severe ulcerating reflux esophagitis: 10-20 mg once daily for 4-12 weeks

Administration

  • IV Injection for prophylaxis of acid aspiration
  • IV Infusion for duodenal ulcer, gastric ulcer or reflux oesophagitis

Interaction

  • Decreased intragastric acidity may reduce absorption of ketoconazole
  • Metabolized in the liver through cytochrome P450
  • May delay the elimination of diazepam, phenytoin, and warfarin

Contraindications

  • Known hypersensitivity to Omeprazole

Side Effects

  • Skin rash, urticaria, and pruritus
  • Diarrhoea and headache
  • Gastrointestinal reactions like constipation and nausea/vomiting
  • Dizziness, light headedness, and feeling faint

Pregnancy & Lactation

  • No adverse effects on pregnancy or health of the fetus/newborn child

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and Omeprazole
  • Observational studies suggest an increased risk of osteoporosis-related fractures
  • Atrophic gastritis may occur with long-term use

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat

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