Pantohil 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Goodman pharmaceuticals ltd
Also available as
Pantohil 20 mg tablet

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

  • Proton pump inhibitor
  • Suppresses final step in gastric acid production
  • Covalently binds to H+/K+ATPase enzyme system
  • Inhibits both basal and stimulated gastric acid secretion

Dosage & Administration

  • Oral administration
  • Benign gastric ulcer: 40 mg daily in the morning for 4 weeks
  • Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks
  • Duodenal ulcer: 40 mg daily in the morning for 2 weeks
  • Duodenal ulcer with Helicobacter pylori: Pantoprazole is recommended at a dose of 40 mg twice daily
  • Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily
  • IV Injection: 40 mg once daily for 7-10 days
  • IV Injection for prevention of rebleeding in peptic ulcer: 80 mg IV, followed by 8 mg/hour infusion for 72 hours

Interaction

No significant drug interactions observed in clinical studies

Contraindications

Contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side Effects

  • Well tolerated in both short-term and long-term treatment
  • Common: Headache, diarrhea
  • Rare: Abdominal pain, flatulence, rash, insomnia, hyperglycemia

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • No adequate and well-controlled studies in pregnant women
  • Excreted in human milk

Precautions & Warnings

  • Tablet should not be split, chewed or crushed
  • Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12)
  • May increase the risk of osteoporosis related disorders

Overdose Effects

No known symptoms of overdosage in humans

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

  • IV injection: To be given as a slow intravenous injection; freshly prepared solution should be given slowly over at least 2 to 5 minutes
  • IV infusion: Should be given as an intravenous infusion over a period of approximately 15 minutes

Storage Conditions

Keep in a dry place, away from light and heat; keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg

Common Questions about Pantohil 40 mg Tablet

  • Description of Pantohil 40 mg Tablet
  • Improvement duration
  • Frequency of use
  • Timing of use
  • Storage and disposal instructions
  • Effects on older adults
  • Onset of action
  • Safety
  • Potential for weight gain
  • Side effects
  • Use during pregnancy or breastfeeding
  • What to do if a dose is missed

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