Tajenta-M 2.5 mg+500 mg (Tablet)

Title and Category

• Tajenta-M Tablet
• Combination Oral hypoglycemic preparations

Dimensions

• Standard tablet size

Color Options

• No specific color options

Functions

• Improves glycemic control in adults with type 2 diabetes mellitus
• Adjunct to diet and exercise
• Inhibits DPP-4 enzyme
• Stimulates insulin release in a glucose-dependent manner
• Decreases glucagon secretion
• Lowers both basal and postprandial plasma glucose
• Decreases hepatic glucose production
• Improves insulin sensitivity
• Indicated as an immediate release or extended release tablet

Materials

• Contains Linagliptin and Metformin Hydrochloride

Technical Specifications

• Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride (immediate release)
• Maximum recommended total daily dose of Linagliptin 5 mg and Metformin Hydrochloride 2000 mg (extended release)

Design Elements

• Film-coated tablets
• Immediate release or extended release format

Usability Features

• Individualized dosage based on effectiveness and tolerability
• Gradual dose escalation
• Once daily administration (extended release)

Interaction

• Potential interaction with cationic drugs
• Interaction with carbonic anhydrase inhibitors
• Interaction with inducers of P-glycoprotein and CYP3A4 enzymes
• Effect on drugs affecting glycemic control

Contraindications

• Contraindicated in patients with renal impairment
• Contraindicated in acute or chronic metabolic acidosis
• Contraindicated in hypersensitivity to Linagliptin or Metformin Hydrochloride

Side Effects

• Common side effects include nasopharyngitis and diarrhea
• Increased risk of hypoglycemia in patients treated with Tajenta-M and sulfonylureas

Pregnancy & Lactation

• No adequate and well-controlled studies in pregnant women
• Caution advised during pregnancy and lactation

Precautions & Warnings

• Discontinue in case of lactic acidosis or suspected pancreatitis
• Temporary discontinuation for radiologic studies or surgical procedures
• Monitoring of Vitamin B12 levels
• Potential for lactic acidosis under certain conditions

Overdose Effects

• Usual supportive measures in case of overdose
• Dialyzable in case of Metformin Hydrochloride overdose

Storage Conditions

• Store in a cool & dry place (below 30°C)
• Protect from light & moisture
• Keep out of reach of children

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