Ursohil 150 mg (Tablet)
Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00
Medicine Details
Category | Details |
---|---|
Generic | Ursodeoxycholic acid |
Company | Goodman pharmaceuticals ltd |
Also available as |
Indications
- Cholestasis (Jaundice)
- Viral Hepatitis
- Alcoholic Fatty Liver
- Primary Billiary Cirrhosis (PBC)
- Primary Sclerosing Cholangitis (PSC)
- Dissolution of Gallstones
- Non-Alcoholic Steato Hepatitis (NASH)
Description
Used to reduce the cholesterol saturation of bile and to promote the dissolution of gallstones.
Pharmacology
- Decreases cholesterol absorption
- Suppresses liver cholesterol synthesis
- Promotes the formation of liquid cholesterol crystal complexes
- Protects cholangiocytes against cytotoxicity of hydrophobic bile acids
- Completely absorbed in the upper intestine
- Biologic half life ranges from 3.5-5.8 days
Dosage & Administration
Doses for various conditions including Dissolution of Gall stones, Primary Billiary Cirrhosis, Acute Viral Hepatitis, Alcoholic Fatty Liver, Primary Sclerosing Cholangitis, and Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis
Interaction
Should not be used with drugs that increase bile cholesterol, and should be avoided with bile-acid binding drugs
Contraindications
- Non-functioning gall-bladder
- Calcified and pigmented gallstones
- Inflammatory bowel disease
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Gallstone opacilication
- Pruritus
Pregnancy & Lactation
Pregnancy category B, effectively used for cholestasis of pregnancy, no documented problems in humans regarding breastfeeding
Precautions & Warnings
Should be used cautiously in those with liver disease
Therapeutic Class
Anti-gallstones drugs: Bile Acids
Storage Conditions
Store below 25°C, protect from light and moisture, keep out of reach of children