Caprolex 1 gm/5 ml (Injection)

5 ml ampoule: ৳ 24.88 (1 x 5: ৳ 124.41)

Medicine Details

Category Details
Generic Aminocaproic acid
Company Techno drugs ltd
Also available as
Caprolex 2 gm injection

Title

  • Caprolex

Categories

  • Medicines
  • Pharmaceuticals
  • Hemostatic Agents

Description

  • Used to treat excessive postoperative bleeding
  • Can be administered orally or intravenously
  • Can reduce blood loss in patients undergoing coronary artery bypass grafting
  • Can be used to treat overdose and/or toxic effects of thrombolytic pharmacologic agents

Indications

  • Treatment of excessive postoperative bleeding
  • Oral and intravenous administration
  • Reduction of blood loss in coronary artery bypass grafting
  • Treatment of thrombolytic pharmacologic agent overdose/toxic effects

Pharmacology

  • Exerts fibrinolysis-inhibitory effects via inhibition of plasminogen activators and antiplasmin activity

Dosage & Administration

  • Dosage adjustment according to severity of hemorrhagic event
  • Rapid clearance by renal route necessitating repeated administration every 4-6 hours
  • Average daily dose of 8-16 gm
  • Equally effective by mouth and intravenous injection
  • Administration continued until complete cessation of all symptoms

Contraindications

  • Not to be used when evidence of active intravascular clotting process
  • Caution needed in distinguishing primary fibrinolysis from disseminated intravascular coagulation (DIC) before administration
  • Various tests to differentiate primary fibrinolysis from DIC
  • Should not be used in the presence of DIC without concomitant heparin

Side Effects

  • Mild muscle pain or weakness
  • Headache
  • Nausea, vomiting, stomach pain, diarrhea
  • Decreased amount of semen in men
  • Stuffy nose, watery eyes
  • Vision problems, ringing in ears
  • Mild skin rash

Pregnancy & Lactation

  • Pregnancy Category C
  • No animal reproduction studies conducted
  • Uncertain if it can cause fetal harm or affect reproduction capacity
  • Should be given to a pregnant woman only if clearly needed

Precautions & Warnings

  • Safety and efficacy not established in patients younger than 18 years

Therapeutic Class

  • Anti-fibrinolytic drugs
  • Haemostatic drugs

Storage Conditions

  • Store in cool, dry place
  • Protected from light
  • Suspension to be stored below 30°C
  • Keep out of reach of children

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