Pulmosis 534 mg (Tablet)
Unit Price: ৳ 80.00 (2 x 10: ৳ 1,600.00)
Strip Price: ৳ 800.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pirfenidone |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of mild to moderate Idiopathic Pulmonary Fibrosis (IPF) in adults
Pharmacology
- Anti-inflammatory
- Antioxidant
- Anti-fibrotic properties
- Improves lung function
- Reduces acute exacerbations in IPF patients
- Suppresses TGF-beta1
- Downregulates pro-inflammatory cytokines
Dosage & Administration
- Orally administered with food
- Titration for initiating treatment
- Dose adjustments for gastrointestinal events
- Dose adjustments for photosensitivity reaction or rash
- Dose adjustments for hepatic function
Interaction
- Moderate and strong inhibitors of CYP1A2
- Use with food
- Reduced incidence of adverse reactions in fed group
Contraindications
- Hypersensitivity to active substance or excipients
- Concomitant use of fluvoxamine
- Severe hepatic impairment or end stage liver disease
- Severe renal impairment or end stage renal disease
Side Effects
- Nausea
- Rash
- Abdominal pain
- Upper respiratory tract infection
- Diarrhea
- Fatigue
- Headache
- Dyspepsia
- Dizziness
- Vomiting
- Anorexia
- Gastroesophageal reflux disease
- Sinusitis
- Insomnia
- Weight decrease
- Arthralgia
- Photosensitivity reaction
- Decreased appetite
- Pruritus
- Asthenia
- Dysgeusia
- Non-cardiac chest pain
Pregnancy & Lactation
- No data on use in pregnant women
- Preferable to avoid use during pregnancy
- Unknown excretion in human milk
- Potential for accumulation in amniotic fluid and milk
- No effects on fertility and reproductive performance in rats
Precautions & Warnings
- Elevated liver enzymes
- Photosensitivity and rash precautions
- Gastrointestinal disorders precautions
Use in Special Populations
- Safety and efficacy not known in children & adolescents
- Monitor for adverse reactions in hepatic impairment
- Monitor for adverse reactions in renal impairment
- Decreased exposure noted in smokers
Overdose Effects
- Limited clinical experience with overdose
- Mild, transient adverse reactions
Therapeutic Class
- Immunosuppressant
Storage Conditions
- Store in cool & dry place
- Protect from light & moisture
- Keep out of reach of children
Related Brands
- Pulmosis 267 mg (Capsule) - incepta-pharmaceuticals-ltd
- Pulfibro 267 mg (Tablet) - unimed-unihealth-pharmaceuticals-ltd
- Pulfibro 801 mg (Tablet) - unimed-unihealth-pharmaceuticals-ltd
- Pulfibro 534 mg (Tablet) - unimed-unihealth-pharmaceuticals-ltd
- Pulmosis 801 mg (Tablet) - incepta-pharmaceuticals-ltd