Atasin 10 mg (Tablet)
Unit Price: ৳ 12.00 (5 x 10: ৳ 600.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Aci limited |
| Also available as |
Title
- Atasin 10 mg Tablet
Categories
- Medicine
- Cholesterol management
- Cardiovascular health
Description
- Atasin is indicated for reducing total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides.
- It is to be used as an adjunct to diet when other non-pharmacological measures are inadequate.
- Atorvastatin is a selective inhibitor of HMG-CoA reductase, lowering plasma cholesterol and lipoprotein levels.
- Dosage ranges from 10 to 80 mg once daily, adjusted according to individual response.
- Common side effects include constipation, flatulence, dyspepsia, abdominal pain, infection, headache, and myalgia.
- Atorvastatin is contraindicated during pregnancy and lactation, and in patients with active liver disease or unexplained elevations of serum transaminases.
Indications
- Reduction of total cholesterol and LDL cholesterol in heterozygous and homozygous familial hypercholesterolaemia
- Reduction of elevated cholesterol and triglycerides in patients with mixed dyslipidemia
- Treatment of patients with elevated serum triglyceride levels in hypertriglyceridaemia
- Treatment of patients with dysbetalipoproteinaemia
- Reduction of cardiac ischaemic events in patients with coronary artery disease
- Reduction of cholesterol levels associated with diabetes mellitus or renal transplantation
Pharmacology
- Atorvastatin is rapidly absorbed after oral administration with maximum plasma concentrations within 1 to 2 hours
- Mean volume of distribution of Atorvastatin is approximately 381 liters with 98% plasma protein binding
- Extensively metabolized to ortho- and parahydroxylated derivatives
- Atorvastatin and its metabolites are eliminated primarily in bile
Dosage & Administration
- Adults: Usually 10 mg once daily; may be increased to max. 80 mg once daily if necessary
- Children (10-18 years): Initially 10 mg once daily, increased to max. 20 mg once daily if necessary
Interactions
- Risk of myopathy increased with concurrent administration of cyclosporine, fibric acid derivatives, niacin, erythromycin, and azole antifungals
- Plasma concentrations of atorvastatin decreased when coadministered with antacid suspension or increased when coadministered with digoxin, erythromycin, or oral contraceptives
Contraindications
- Hypersensitivity to any component of the medication
- Active liver disease or unexplained persistent elevations of serum transaminases
- History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors
Side Effects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Infection
- Headache
- Back pain
- Rash
- Asthenia
- Arthralgia
- Myalgia
Pregnancy & Lactation
- Atorvastatin is contraindicated during pregnancy
- Not known whether atorvastatin or its metabolites are excreted in human milk
Precautions & Warnings
- Liver function tests should be performed before the initiation of treatment and periodically thereafter
- Atasin should be used with caution in patients who consume substantial quantities of alcohol or have a history of liver disease
Use in Special Populations
- Plasma concentrations of Atasin are higher in healthy elderly subjects than in young adults
- No clinically significant difference in LDL-C reduction with Atasin between men and women
- Renal disease has no influence on the plasma concentrations or LDL-C reduction of Atasin
- In patients with chronic alcoholic liver disease, plasma concentrations of Atasin are markedly increased
Overdose Effects
- Specific treatment is not available for atorvastatin overdose
- Liver function tests should be performed and serum CK levels should be monitored
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C33H35FN2O5
Common Questions
- What is Atasin 10 mg Tablet?
- How should I take Atasin 10 mg Tablet?
- What are the uses of Atasin 10 mg Tablet?
- What are the Side Effects of Atasin 10 mg Tablet?
- What are the instructions for storage and disposal Atasin 10 mg Tablet?
- Is Atasin 10 mg Tablet used for lowering cholesterol?
- Will taking Atasin 10 mg Tablet increase my risk of diabetes?
- For how long do I need to take Atasin 10 mg Tablet? Is it safe for long-term use?
- Does Atasin 10 mg Tablet cause weight loss?
- Can I stop taking Atasin 10 mg Tablet?
- Does Atasin 10 mg Tablet cause memory loss?
- Does Atasin 10 mg Tablet make you tired?
- Can Atasin 10 mg Tablet be prescribed to children?
- Is Atasin 10 mg Tablet a blood thinner?